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About This Item
Empirical Formula (Hill Notation):
C28H39N5O8
CAS Number:
Molecular Weight:
573.64
UNSPSC Code:
12352204
PubChem Substance ID:
MDL number:
InChI
1S/C28H39N5O8/c1-18(2)14-20(25(36)29-15-23(34)33-13-7-11-22(33)27(38)39)31-26(37)21-10-6-12-32(21)24(35)16-30-28(40)41-17-19-8-4-3-5-9-19/h3-5,8-9,18,20-22H,6-7,10-17H2,1-2H3,(H,29,36)(H,30,40)(H,31,37)(H,38,39)
SMILES string
CC(C)CC(NC(=O)C1CCCN1C(=O)CNC(=O)OCc2ccccc2)C(=O)NCC(=O)N3CCCC3C(O)=O
InChI key
DGRDYZZPQWDRBB-UHFFFAOYSA-N
form
solid
storage temp.
2-8°C
General description
A substrate for collagenase.
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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K Nomura et al.
Biochemistry, 30(25), 6115-6123 (1991-06-25)
The sea urchin hatching enzyme (HEz) is a protease capable of dissolving the fertilization envelope that surrounds the embryo as a protective coat during early development. We have now purified a 37-kDa active enzyme from the supernatant fluid of hatched
Simultaneous analyses of clostridium collagenase and neutral proteinase activities with a single synthetic substrate.
K Nomura
Analytical biochemistry, 107(1), 96-102 (1980-09-01)
T Morita et al.
Journal of biochemistry, 82(5), 1495-1498 (1977-11-01)
Twenty peptide-4-methylcoumarin amides (MCA) were newly synthesized and tested as possible substrates for alpha-thrombin, factor Xa, kallikreins, urokinase, and plasmin. These fluorogenic peptides contained arginine-MCA as the carboxyl-terminus. Release of 7-amino-4-methylcoumarin was determined fluorometrically. Of these peptides, the following were
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