Key Documents

View All Documentation

C0742

CKI-7 dihydrochloride

Name: CKI-7 dihydrochloride
Brand: SIGMA

≥98% (HPLC), solid, CK1 inhibitor

Synonym(s):

N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulphonamide dihydrochloride

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):

C₁₁H₁₂ClN₃O₂S · 2HCl

CAS Number:

1177141-67-1

Molecular Weight:

358.67

UNSPSC Code:

12352200

PubChem Substance ID:

24724430

NACRES:

NA.77

MDL number:

MFCD00897689

Assay:

≥98% (HPLC)

Form:

solid

Quality level:

100

Storage condition:

desiccated

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

Product Name

CKI-7 dihydrochloride, ≥98% (HPLC), solid

Quality Level

100

assay

≥98% (HPLC)

form

solid

storage condition

desiccated

color

white to light tan

solubility

H₂O: >5 mg/mL

storage temp.

−20°C

SMILES string

Cl[H].Cl[H].NCCNS(=O)(=O)c1ccc(Cl)c2ccncc12

InChI

1S/C11H12ClN3O2S.2ClH/c12-10-1-2-11(18(16,17)15-6-4-13)9-7-14-5-3-8(9)10;;/h1-3,5,7,15H,4,6,13H2;2*1H

InChI key

JUAVTXYOCISSSL-UHFFFAOYSA-N

Description

Biochem/physiol Actions

CKI-7 is a CK1 inhibitor; also inhibits SGK, S6K1 and MSK1.

CKI-7 is a CK1 inhibitor; also inhibits SGK, S6K1 and MSK1. CKI-7 inhibits SGK as potently as CK1. IC₅₀ = 6 μM.

Disclaimer

Material is hygroscopic

pictograms

GHS06

signalword

Danger

hcodes

H301

pcodes

P264 - P270 - P301 + P310 - P405 - P501

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

0000535172

0000492838

0000405882

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Comparative effect of pioglitazone, quercetin and hydroxy citric acid on the status of lipid peroxidation and antioxidants in experimental non-alcoholic steatohepatitis.

K M Surapaneni et al.

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 65(1), 67-74 (2014-03-14)

Oxidative stress is one of the key mechanisms responsible for liver damage and disease progression in non-alcoholic steatohepatitis (NASH). Antioxidants try to combat the oxidative stress and minimise the oxidative stress. In this study, the comparative effect of pioglitazone, quercetin

Reliability and validity of mobile teledermatology in human immunodeficiency virus-positive patients in Botswana: a pilot study.

Rahat S Azfar et al.

JAMA dermatology, 150(6), 601-607 (2014-03-14)

Mobile teledermatology may increase access to care. To determine whether mobile teledermatology in human immunodeficiency virus (HIV)-positive patients in Gaborone, Botswana, was reliable and produced valid assessments compared with face-to-face dermatologic consultations. Cross-sectional study conducted in outpatient clinics and public

Radiation therapy for angiosarcoma of the scalp: treatment outcomes of total scalp irradiation with X-rays and electrons.

Masaharu Hata et al.

Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 190(10), 899-904 (2014-03-14)

Wide surgical excision is the standard treatment for angiosarcoma of the scalp, but many patients are inoperable. Therefore, we investigated the outcome of radiation therapy for angiosarcoma of the scalp. Seventeen patients with angiosarcoma of the scalp underwent radiation therapy

View All Related Papers

Global Trade Item Number

SKU	GTIN
C0742-25MG	04061832445182
C0742-5MG	04061833451557