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C0742

CKI-7 dihydrochloride

Name: CKI-7 dihydrochloride
Brand: SIGMA

≥98% (HPLC), solid, CK1 inhibitor

Synonym(s):

N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulphonamide dihydrochloride

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About This Item

Empirical Formula (Hill Notation):

C₁₁H₁₂ClN₃O₂S · 2HCl

CAS Number:

1177141-67-1

Molecular Weight:

358.67

UNSPSC Code:

12352200

PubChem Substance ID:

24724430

NACRES:

NA.77

MDL number:

MFCD00897689

Assay:

≥98% (HPLC)

Form:

solid

Storage condition:

desiccated

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Properties

Product Name

CKI-7 dihydrochloride, ≥98% (HPLC), solid

Quality Segment

100

assay

≥98% (HPLC)

form

solid

storage condition

desiccated

color

white to light tan

solubility

H₂O: >5 mg/mL

storage temp.

−20°C

SMILES string

Cl[H].Cl[H].NCCNS(=O)(=O)c1ccc(Cl)c2ccncc12

InChI

1S/C11H12ClN3O2S.2ClH/c12-10-1-2-11(18(16,17)15-6-4-13)9-7-14-5-3-8(9)10;;/h1-3,5,7,15H,4,6,13H2;2*1H

InChI key

JUAVTXYOCISSSL-UHFFFAOYSA-N

Description

Biochem/physiol Actions

CKI-7 is a CK1 inhibitor; also inhibits SGK, S6K1 and MSK1.

CKI-7 is a CK1 inhibitor; also inhibits SGK, S6K1 and MSK1. CKI-7 inhibits SGK as potently as CK1. IC₅₀ = 6 μM.

Disclaimer

Material is hygroscopic

pictograms

GHS06

signalword

Danger

hcodes

H301

pcodes

P264 - P270 - P301 + P310 - P405 - P501

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c