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Merck
CN

C0755

Conalbumin from chicken egg white

Substantially iron-free

Synonym(s):

Ovotransferrin

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About This Item

CAS Number:
1391-06-6
UNSPSC Code:
12352202
EC Number:
215-727-0
NACRES:
NA.25
MDL number:
MFCD00130856

Key Documents

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Product Name

Conalbumin from chicken egg white, Substantially iron-free

biological source

chicken egg white

assay

≥98% (agarose gel electrophoresis)

form

powder

technique(s)

protein quantification: suitable

UniProt accession no.

P02789

storage temp.

−20°C

Quality Level

200

Gene Information

chicken ... TF(396241)

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Application

Conalbumin from chicken egg white has been used:
  • as ovotransferrin standard in 96?well microplate assay to investigate on ovotransferrin-like activity in the plasma of wild birds
  • to examine its effects on osteoclastogenesis
  • to study its partitioning in aqueous two-phase systems

Biochem/physiol Actions

Conalbumin/ovotransferrin plays a key role in avian natural immunity. It has the ability to prevent bacterial growth and possesses immunomodulatory functions. Ovotransferrin also exhibits antimicrobial and antioxidant activities.

General description

Conalbumin is an iron-binding protein. It is mainly present in the egg white of hen. It is also termed as ovotransferrin. It is a member of the transferrin iron-binding glycoproteins family. Ovotransferrin is also known an an acute?phase protein (APP)in some organisms. It is the second main protein found in egg white.

pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H317,H334

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Regulatory Information

动植物来源生物产品
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Certificates of Analysis (COA)

Lot/Batch Number
0000493695
0000493695
0000465773
0000465775
0000465774

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A simple assay for measurement of ovotransferrin-a marker of inflammation and infection in birds
Horrocks NPC, et al.
Methods in Ecology and Evolution, 2(5), 518-526 (2011)
Siderophores and transferrins
Dertz EA and Raymond KN
ChemInform, 35(49), no-no (2004)
Bacterial iron metabolism in infection and immunity
Microbial iron metabolism, 517-551 (1974)
Egg White Ovotransferrin Attenuates RANKL-Induced Osteoclastogenesis and Bone Resorption
Shang N and Wu J
Nutrients, 11(9), 2254-2254 (2019)
Physiological roles of ovotransferrin
Giansanti F, et al.
Biochimica et biophysica acta. General subjects, 1820(3), 218-225 (2012)
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Articles

HPLC Analysis of Protein Standards (1) on BIOshell™ A400 Protein C4

For use as a marker in SDS-PAGE; Albumin from chicken egg white, For use as a marker in SDS-PAGE; L-Lactic Dehydrogenase from rabbit muscle, Type XI, lyophilized powder, 600-1,200 units/mg protein

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