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Merck
CN

C1006

Sigma-Aldrich

Cytidine 5′-monophosphate disodium salt

≥99%, synthetic, crystalline

Synonym(s):

C-5′-P, CMP

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About This Item

Linear Formula:
C9H12N3O8PNa2
CAS Number:
6757-06-8
Molecular Weight:
367.16
EC Number:
229-819-3
MDL number:
MFCD00064355
UNSPSC Code:
41106305
PubChem Substance ID:
24892293
NACRES:
NA.51

Key Documents

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Product Name

Cytidine 5′-monophosphate disodium salt, Sigma Grade, ≥99%, crystalline

biological source

synthetic

Quality Level

300

grade

Sigma Grade

Assay

≥99%

form

crystalline

solubility

water: 100 mg/mL, clear to very slightly hazy, colorless to very faintly yellow

storage temp.

2-8°C

SMILES string

[Na].NC1=NC(=O)N(C=C1)C2OC(COP(O)(O)=O)C(O)C2O

InChI

1S/C9H14N3O8P.Na.H/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18;;/h1-2,4,6-8,13-14H,3H2,(H2,10,11,15)(H2,16,17,18);;

InChI key

RCIPNLSOCXMZDD-UHFFFAOYSA-N

Application

Cytidine 5′-monophosphate disodium salt has been used:
  • in nucleotide stock solution
  • as an ectonucleotidase (ENTase) inhibitor to probe 5′-ENTase activity in cortical neurons
  • in in vitro studies to estimate its effect on growth response of selected bacteria strains that dominate the piglets′ small intestine

Biochem/physiol Actions

Cytidine 5′-monophosphate (CMP) is used as a substrate of uridine monophosphate (UMP)/cytidine monophosphate (CMP) kinase (EC 2.7.4.4) to form CDP which upon phosphorylation to CTP supports DNA and RNA biosynthesis.
Cytidine monophosphate (CMP) serve as a nucleotide carrier for sugars.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
WXBF6392V
WXBF6420V
WXBF5515V
WXBD7001V
WXBF3943V

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Vaur P, et al.
Faseb Journal (2017)
Charuni A Amarasekara et al.
Journal of chromatography. A, 1638, 461892-461892 (2021-01-22)
With advances in the design and fabrication of nanofluidic devices during the last decade, there have been a few reports on nucleic acid analysis using nanoscale electrophoresis. The attractive nature of nanofluidics is the unique phenomena associated with this length
Carbohydrate Metabolism III: Glycoproteins, Glycolipids, GPI Anchors, Proteoglycans, and Peptidoglycans
Medical Biochemistry, 307-330 (2002)
Balvinder Dhaliwal et al.
Acta crystallographica. Section F, Structural biology and crystallization communications, 62(Pt 8), 710-715 (2006-08-02)
The crystal structure of Staphylococcus aureus cytidine monophosphate kinase (CMK) in complex with cytidine 5'-monophosphate (CMP) has been determined at 2.3 angstroms resolution. The active site reveals novel features when compared with two orthologues of known structure. Compared with the
Anaerobic growth of Bacillus mojavensis and Bacillus subtilis requires deoxyribonucleosides or DNA
Folmsbee MJ, et al.
Applied and Environmental Microbiology, 70(9) (2004)
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