C1011
N-Cyclohexyl-N′-(2-morpholinoethyl)carbodiimide metho-p-toluenesulfonate
≥97% (CHN)
Synonym(s):
N-Cyclohexyl-N′-(β-[N-methylmorpholino]ethyl)carbodiimide p-toluenesulfonate, CMC, CME-CDI
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About This Item
Empirical Formula (Hill Notation):
C14H26N3O · C7H7O3S
CAS Number:
Molecular Weight:
423.57
EC Number:
219-650-3
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
3872192
MDL number:
assay
≥97% (CHN)
form
powder
technique(s)
ligand binding assay: suitable
color
white
mp
109-111 °C
application(s)
peptide synthesis
storage temp.
−20°C
SMILES string
Cc1ccc(cc1)S([O-])(=O)=O.C[N+]2(CCOCC2)CCN=C=NC3CCCCC3
InChI
1S/C14H26N3O.C7H8O3S/c1-17(9-11-18-12-10-17)8-7-15-13-16-14-5-3-2-4-6-14;1-6-2-4-7(5-3-6)11(8,9)10/h14H,2-12H2,1H3;2-5H,1H3,(H,8,9,10)/q+1;/p-1
InChI key
GBCAVSYHPPARHX-UHFFFAOYSA-M
Application
Water-soluble condensing reagent for peptide synthesis, reagent used for coupling ligands to carriers in affinity chromatography.
Biochem/physiol Actions
N-Cyclohexyl-N′-(2-morpholinoethyl)carbodiimide (CMCT) selectively modifies/derivitizes all pseudouridine, thiouridine and 2-methylthio-6-isopentenyladenosine nucleosides for detection by methods such as matrix-assisted laser desorption/ionization mass spectrometry. CMCT, a water-soluble condensing reagent for peptide synthesis, is used as a reagent for coupling ligands to carriers in affinity chromatography.
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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