C1145
Cholesterol–PEG 600
Synonym(s):
Cholesterol, water soluble from sheep, Cholesteryl-polyethylene glycol 600 sebacate, Polyethylene glycol 600 mono(cholesteryl) ether sebacate, Polyoxyethyl-cholesteryl sebacate
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About This Item
Form:
solid
Quality level:
form
solid
Quality Level
extent of labeling
≥20% cholesterol
color
light yellow
solubility
H2O: 60 mg/mL
shipped in
dry ice
storage temp.
−20°C
General description
Cholesterol is one of the important constituent of all membranes. It is made up of a hydrophobic, planar, a polar hydroxyl group, fused-ring nucleus and a short hydrocarbon tail.
Application
Cholesterol-PEG 600 has been used to evaluate its ability to induce apoptosis in vascular smooth muscle cells. It has also been used to restore cholesterol following depletion by methyl β-cyclodextrin.
Biochem/physiol Actions
Cholesterol acts as an antecedent of steroid hormones. It plays a key role in fetal growth and in brain development.
Physical form
semisolid to solid
Preparation Note
Prepared by method of Proksch, G.J., and Bonderman, D.P., Clin. Chem., 24, 1924 (1978).
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Articles
Discover Bioactive Small Molecules for Lipid Signaling Research
Linda Shaw et al.
Cardiovascular research, 69(4), 825-835 (2006-02-09)
A close association of caveolae and sarcoplasmic reticulum (SR) has been suggested to be important for contractile activation of smooth muscle. Here, we investigate the presence of such arrangements in pressurised resistance arteries and examine the influence of two agents
M Absi et al.
British journal of pharmacology, 151(3), 332-340 (2007-04-24)
The small and intermediate conductance, Ca2+-sensitive K+ channels (SK(Ca) and IK(Ca), respectively) which are pivotal in the EDHF pathway may be differentially activated. The importance of caveolae in the functioning of IK(Ca) and SK(Ca) channels was investigated. The effect of
The Lipids of Biological Membranes
The Membranes of Cells null
Global Trade Item Number
| SKU | GTIN |
|---|---|
| C1145-5G | 04061833075937 |
| C1145-250MG | 04061833075913 |
| C1145-1G | 04061826690093 |
| C1145-500MG | 04061833461297 |