C1629
Choline bitartrate
Acyl group acceptor, powder
Synonym(s):
2-(Hydroxyethyl)trimethylammonium bitartrate
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About This Item
Empirical Formula (Hill Notation):
C9H19NO7
CAS Number:
Molecular Weight:
253.25
EC Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
Product Name
Choline bitartrate,
form
powder
Quality Level
SMILES string
[O-]C([C@H](O)[C@@H](O)C(O)=O)=O.C[N+](C)(C)CCO
InChI
1S/C5H14NO.C4H6O6/c1-6(2,3)4-5-7;5-1(3(7)8)2(6)4(9)10/h7H,4-5H2,1-3H3;1-2,5-6H,(H,7,8)(H,9,10)/q+1;/p-1/t;1-,2-/m.1/s1
InChI key
QWJSAWXRUVVRLH-LREBCSMRSA-M
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Related Categories
General description
Choline acetyltransferase substrate
Application
Choline bitartrate has been used as one of the components in experimental diets to study the effects on reproductive processes and on bone genes during gestation and lactation.
Biochem/physiol Actions
Acyl group acceptor
Choline bitartrate is known to serve as a dietary supplement. Choline acts as a precursor for acetylcholine synthesis.
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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No acute effects of choline bitartrate food supplements on memory in healthy, young, human adults
Lippelt DP, et al.
PLoS ONE, 11(6), e0157714-e0157714 (2016)
Margaret A Mouat et al.
Cells, 11(11) (2022-06-11)
Understanding the neurogenic causes of obesity may reveal novel drug targets to counter the obesity crisis and associated sequelae. Here, we investigate whether the deletion of GPR37L1, an astrocyte-specific orphan G protein-coupled receptor, affects whole-body energy homeostasis in mice. We
O T Pantako et al.
Reproduction, nutrition, development, 41(3), 227-238 (2001-10-11)
The effects of two dietary proteins on alpha-amino acids, calcium and phosphorus concentrations in plasma, stomach and intestine were investigated in rats trained to consume, in a single two-hour daily meal, diets containing a-lactalbumin (alpha-la) or whey protein concentrate (WPC)
Yumna Zia et al.
The Journal of nutrition, 148(10), 1513-1520 (2018-10-04)
Phosphatidylethanolamine N-methyltransferase (PEMT) converts phosphatidylethanolamine to phosphatidylcholine. Pemt-/-/low density lipoprotein receptor (Ldlr)-/- mice have significantly reduced plasma lipids and are protected against atherosclerosis. Recent studies have shown that choline can be metabolized by the gut flora into trimethylamine-N-oxide (TMAO), which
Jacob H Murray et al.
Journal of medicinal chemistry, 66(6), 3876-3895 (2023-03-08)
Small-molecule mitochondrial uncouplers are gaining recognition as potential therapeutics for metabolic diseases such as obesity, diabetes, and nonalcoholic steatohepatitis (NASH). Specifically, heterocycles derived from BAM15, a potent and mitochondria-selective uncoupler, have yielded promising preclinical candidates that are efficacious in animal
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