Key Documents

View All Documentation

C1835

(S)-(+)-4-Carboxyphenylglycine

Name: (<I>S</I>)-(+)-4-Carboxyphenylglycine
Brand: SIGMA

Synonym(s):

(S)-α-Amino-4-carboxyphenylacetic acid, L-α-(4-Carboxyphenyl)glycine, S-4CPG

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):

C₉H₉NO₄

CAS Number:

134052-73-6

Molecular Weight:

195.17

UNSPSC Code:

12352103

MDL number:

MFCD00216831

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

solubility

0.1 M NaOH: 15 mg/mL

Description

Biochem/physiol Actions

Competitive mGluR₁ metabotropic glutamate receptor antagonist; mGluR₂ metabotropic glutamate receptor agonist.

Regulatory Information

新产品

This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

026H0148

089H1383

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Competitive antagonism at metabotropic glutamate receptors by (S)-4-carboxyphenylglycine and (RS)-alpha-methyl-4-carboxyphenylglycine.

S A Eaton et al.

European journal of pharmacology, 244(2), 195-197 (1993-01-15)

Two phenylglycine derivates, (S)-4-carboxyphenylglycine and (RS)-alpha-methyl-4-carboxyphenylglycine, competitively antagonised (1S,3R)-1-aminocyclopentane-1,3-dicarboxylate (ACPD)-stimulated phosphoinositide hydrolysis in rat cerebral cortical slices. The same phenylglycine derivatives selectively antagonized ACPD-induced depolarization in neonatal rat spinal motoneurones and rate thalamic neurones relative to depolarization or excitation induced

Pharmacological analysis of carboxyphenyl-glycines at metabotropic glutamate receptors.

Cavanni, et al.

Eur. J. Pharmacol., Molec. Pharmacol. Sec., 269, 9-9 (1994)

Phenylglycine derivatives as new pharmacological tools for investigating the role of metabotropic glutamate receptors in the central nervous system.

E F Birse et al.

Neuroscience, 52(3), 481-488 (1993-02-01)

The possible roles of G-protein coupled metabotropic glutamate receptors in central nervous function are currently the focus of intensive investigation. The complexity of effects produced by agonists at these receptors probably reflects the activity of a range of sub-types. The