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Merck
CN

C213280

DMT-2′Fluoro-dC(ac) Phosphoramidite

configured for PerkinElmer, configured for Polygen

Synonym(s):

DMT-2′-F-dC(ac) amidite

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About This Item

Empirical Formula (Hill Notation):
C41H49FN5O8P
CAS Number:
Molecular Weight:
789.83
UNSPSC Code:
41116105
NACRES:
NA.21
MDL number:
Assay:
≥99% (31P-NMR), ≥99.0% (reversed phase HPLC)
Form:
powder
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biological source

non-animal source (no BSE/TSE risk)

Quality Segment

product line

Proligo Reagents

assay

≥99% (31P-NMR), ≥99.0% (reversed phase HPLC)

form

powder

technique(s)

oligo synthesis: suitable

impurities

≤0.3% water content (Karl Fischer), ≤0.5% P(III) Impurities 100-169ppm (31P-NMR), ≤0.5% single Impurity (reversed phase HPLC), ≤3% residual Solvent content

color

white to off-white

λ

conforms (UV/VIS Identity)

suitability

conforms to structure for H-NMR, conforms to structure for LC-MS

compatibility

configured for PerkinElmer, configured for Polygen

nucleoside profile

base: deoxycytidine
base protecting group: acetyl
2' protecting group: fluoro
5' protecting group: DMT
deprotection: fast/standard

storage temp.

−20°C

SMILES string

COc1ccc(cc1)C(OC[C@H]2O[C@H]([C@H](F)[C@@H]2OP(OCCC#N)N(C(C)C)C(C)C)N3C=CC(NC(C)=O)=NC3=O)(c4ccccc4)c5ccc(OC)cc5

InChI

1S/C41H49FN5O8P/c1-27(2)47(28(3)4)56(53-25-11-23-43)55-38-35(54-39(37(38)42)46-24-22-36(44-29(5)48)45-40(46)49)26-52-41(30-12-9-8-10-13-30,31-14-18-33(50-6)19-15-31)32-16-20-34(51-7)21-17-32/h8-10,12-22,24,27-28,35,37-39H,11,25-26H2,1-7H3,(H,44,45,48,49)/t35-,37-,38-,39-,56?/m1/s1

InChI key

CNFKJHKDSRXNFL-UTXREMQHSA-N



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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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