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C2851

Anti-CaM Kinase IV (CaMKIV) (AY-18) antibody produced in rabbit

Name: Anti-CaM Kinase IV (CaMKIV) (AY-18) antibody produced in rabbit
Brand: SIGMA

IgG fraction of antiserum, buffered aqueous solution

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About This Item

UNSPSC Code:

12352203

NACRES:

NA.44

MDL number:

MFCD01633080

Conjugate:

unconjugated

Clone:

polyclonal

Application:

ARR, IHC (p), WB

Citations:

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Properties

biological source

rabbit

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 65 kDa

species reactivity

rat, mouse, human

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:10,000 using sections of rat cerebellum, microarray: suitable, western blot: 1:20,000-1:1,000 using rat brain extract and Jurkat, whole cell extract, respectively

UniProt accession no.

Q16566

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... CAMK4(814)
mouse ... Camk4(12326)
rat ... Camk4(25050)

Description

General description

CaM Kinase IV is a Ca²⁺/calmodulin-dependent kinase that belongs to serine/threonine protein kinases family. CaM Kinase IV is expressed in the brain and thymus and is localized in cellular cytoplasm and nucleus. It facilitates the phosphorylation of several substrates in brain like-synapsin I, microtubule associated protein (MAP2), tau and tyrosine hydroxylase. Anti-caM kinase IV (CaMKIV) (AY-18) antibody can be used in western blotting (diluted 1:1000 and 1: 20,000) using human T-cell leukemia Jurkat whole cell extract and rat brain extract. It can also be used in microarray. Rabbit anti-caM kinase IV (CaMKIV) (AY-18) antibody reacts specifically with CaMKIV of rat but cross reacts with human CaMKIV.

Immunogen

Peptide corresponding to amino acids 457-474 of rat CaM kinase IV conjugated to KLH. This sequence has extensive homology to mouse (80%) and human (70%) CaMKIV.

Application

Anti-caM kinase IV (CaMKIV) (AY-18) antibody (diluted 1:500) can be used as a primary antibody in immunohistochemical studies. It can also be used in immunoblotting to detect and localize CAMKIV (65 kDa).

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c