Skip to Content
Merck
CN

C4238

CNS-1102

>98% (HPLC), solid

Synonym(s):

Aptiganel hydrochloride, Cerestat, N-(3-Ethylphenyl)-N-methyl-N’-1-naphthalenylguanidine hydrochloride

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Empirical Formula (Hill Notation):
C20H21N3 · HCl
CAS Number:
137160-11-3
Molecular Weight:
339.86
NACRES:
NA.77
PubChem Substance ID:
24277735
UNSPSC Code:
12352200
MDL number:
MFCD00867728
Assay:
>98% (HPLC)
Form:
solid
Quality level:
100

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

CNS-1102, >98% (HPLC), solid

InChI key

CKAKVKWRMCAYJD-UHFFFAOYSA-N

SMILES string

Cl[H].CCc1cccc(c1)N(C)C(=N)Nc2cccc3ccccc23

InChI

1S/C20H21N3.ClH/c1-3-15-8-6-11-17(14-15)23(2)20(21)22-19-13-7-10-16-9-4-5-12-18(16)19;/h4-14H,3H2,1-2H3,(H2,21,22);1H

assay

>98% (HPLC)

form

solid

color

white

solubility

H2O: soluble 17 mg/mL
DMSO: soluble 20 mg/mL

storage temp.

2-8°C

Quality Level

100

Biochem/physiol Actions

CNS-1102 acts as a neuroprotective agent and might exhibit therapeutic effects against acute stroke and traumatic brain injury.
Noncompetitive NMDA glutamate receptor antagonist.

Features and Benefits

This compound is featured on the Glutamate Receptors (Ion Channel Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

新产品
This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
122K4704

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

K W Muir et al.
Annals of the New York Academy of Sciences, 765, 279-289 (1995-09-15)
The high affinity noncompetitive N-methyl-D-aspartate receptor antagonist CNS 1102 (aptiganel hydrochloride, Cambridge NeuroScience, Cambridge, MA.) is neuroprotective in preclinical models of stroke when administered as pretreatment or up to 60 minutes postischemia, and has potential for treatment of acute stroke

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service