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Merck
CN

C4479

9-Cyclopentyladenine monomethanesulfonate

≥98% (HPLC)

Synonym(s):

9-CP-Ade mesylate, 9-Cyclopentyladenine mesylate

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About This Item

Linear Formula:
C10H13N5 · CH3SO3H
CAS Number:
Molecular Weight:
299.35
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
41106305
MDL number:
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Product Name

9-Cyclopentyladenine monomethanesulfonate, ≥98% (HPLC)

InChI

1S/C10H13N5.CH4O3S/c11-9-8-10(13-5-12-9)15(6-14-8)7-3-1-2-4-7;1-5(2,3)4/h5-7H,1-4H2,(H2,11,12,13);1H3,(H,2,3,4)

SMILES string

CS(O)(=O)=O.Nc1ncnc2n(cnc12)C3CCCC3

InChI key

AJMDRSJHCYQPQI-UHFFFAOYSA-N

assay

≥98% (HPLC)

form

powder

color

white to beige

mp

180-183 °C (lit.)

solubility

H2O: 5 mg/mL, clear

storage temp.

room temp

Quality Level

Biochem/physiol Actions

A stable, cell-permeable, non-competitive adenylyl cyclase inhibitor that targets the P-site domain.
A stable, cell-permeable, non-competitive adenylyl cyclase inhibitor that targets the P-site domain. IC50 = 100 μM in detergent-dispersed rat brain preparation.

Features and Benefits

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

wgk

WGK 3

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Yu Zhang et al.
Frontiers in neuroscience, 14, 364-364 (2020-05-16)
Electrical synapses between neurons exhibit a high degree of plasticity, which makes critical contributions to neuronal communication. The GABAergic parvalbumin-expressing (PV+) neurons in the thalamic reticular nucleus (TRN) interact with each other through electrical and chemical synapses. Plasticity of electrical

Articles

Cyclic nucleotides like cAMP modulate cell function via PKA activation and ion channels.

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