C4743
Monoclonal Anti-Cytochrome P450 3A5 antibody produced in mouse
~2 mg/mL, clone F18 P3 B6, purified immunoglobulin, buffered aqueous solution
Synonym(s):
Anti-CP35, Anti-CYP3A5, Anti-P450PCN3, Anti-PCN3
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About This Item
UNSPSC Code:
12352203
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
F18 P3 B6, monoclonal
form
buffered aqueous solution
mol wt
antigen ~55 kDa
species reactivity
human
concentration
~2 mg/mL
technique(s)
immunohistochemistry: suitable, indirect ELISA: suitable, western blot: 0.5-1.0 μg/mL using human recombinant cytochrome P450 3A5.
isotype
IgG1
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... CYP3A5(1577)
Immunogen
synthetic peptide corresponding to amino acids 380-389 of human cytochrome P450 3A5.
Application
Monoclonal Anti-Cytochrome P450 3A5 antibody produced in mouse is suitable for:
- immunohistochemistry
- indirect ELISA
- western blotting at a concentration of 0.5-1.0 μg/mL using human recombinant cytochrome P450 3A5
Biochem/physiol Actions
Cytochrome P450 enzymes are a super family of heme containing mono-oxygenases that in humans are involved with oxidative metabolism of xenobiotics. This metabolism is the initial step in the biotransformation and elimination of a wide variety of drugs and environmental pollutants from the body. The Cytochrome P450 3A (CYP 3A) family contains several isoforms with the CYP 3A4 isoform contributing most of the family activity and the CYP 3A5, 3A7 and 3A43 being the minor isoforms.
The antibody does not cross react with cytochrome P450 3A4 or 3A7.
Physical form
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
12 - Non Combustible Liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
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