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C4767

β-Cyclodextrin

≥97%

Synonym(s):

beta-Cyclodextrin, Caraway, Cycloheptaamylose, Cyclomaltoheptaose, Schardinger β-Dextrin

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About This Item

Empirical Formula (Hill Notation):
C42H70O35
CAS Number:
7585-39-9
Molecular Weight:
1134.98
UNSPSC Code:
12352302
NACRES:
NA.22
PubChem Substance ID:
24892722
EC Number:
231-493-2
Beilstein/REAXYS Number:
78623
MDL number:
MFCD00078139
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Quality Level

200

biological source

plant

assay

≥97%

form

powder

optical activity

[α]20/D +162±3°, c = 1.5% in H2O

mp

290-300 °C (dec.) (lit.)

solubility

1 M NH4OH: 50 mg/mL

SMILES string

OC[C@H]1O[C@@H]2O[C@H]3[C@H](O)[C@@H](O)[C@H](O[C@@H]3CO)O[C@H]4[C@H](O)[C@@H](O)[C@H](O[C@@H]4CO)O[C@H]5[C@H](O)[C@@H](O)[C@H](O[C@@H]5CO)O[C@H]6[C@H](O)[C@@H](O)[C@H](O[C@@H]6CO)O[C@H]7[C@H](O)[C@@H](O)[C@H](O[C@@H]7CO)O[C@H]8[C@H](O)[C@@H](O)[C@H](O[C@@H]8CO)O[C@H]1[C@H](O)[C@H]2O

InChI

1S/C42H70O35/c43-1-8-29-15(50)22(57)36(64-8)72-30-9(2-44)66-38(24(59)17(30)52)74-32-11(4-46)68-40(26(61)19(32)54)76-34-13(6-48)70-42(28(63)21(34)56)77-35-14(7-49)69-41(27(62)20(35)55)75-33-12(5-47)67-39(25(60)18(33)53)73-31-10(3-45)65-37(71-29)23(58)16(31)51/h8-63H,1-7H2/t8-,9-,10-,11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-/m1/s1

InChI key

WHGYBXFWUBPSRW-FOUAGVGXSA-N

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General description

β-Cyclodextrin is a cyclic oligosaccharide consisting of seven glucose subunits joined by α-(1,4) glycosidic bonds forming a truncated conical structure. It is widely used in food, pharmaceutical, cosmetics, and chemicals industries.

Application

β-Cyclodextrin is used as a complexing agent in drug delivery because it forms an inclusion complex with a drug molecule. The complex of cyclodextrin increases the aqueous solubility, dissolution rate and bioavailability of poorly water-soluble drugs, which is useful for the delivery of the medical agent to a biological system.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
MKDB5626
0000527996
0000527997
0000527996
0000527997

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Study to explore the mechanism to form inclusion complexes of beta-cyclodextrin with vitamin molecules
Saha S, et al.
Scientific Reports, 6, 35764-35764 (2016)
Preparation and characterization of microparticles of ?-cyclodextrin/glutathione and chitosan/glutathione obtained by spray-drying
Webber V, et al.
Food Research International, 105, 432-439 (2018)
Cyclodextrins
Kurkov SV and Loftsson T
The International journal of pharmacy practice, 453, 167-180 (2013)
Use of dehydrated beta-cyclodextrin as pharmaceutical excipient
Martini A, et al.
Drug Development and Industrial Pharmacy, 20, 2381-2393 (1994)
Inclusion complexation of tolbutamide with ?-cyclodextrin and hydroxypropyl-?-cyclodextrin
Veiga F, et al.
Journal of psychosomatic obstetrics and gynaecology, 129, 63-71 (1996)
View All Related Papers

Articles

Cyclodextrins

Techniques for solubilizing metabolically important compounds in aqueous solutions are reviewed.

环糊精

很多重要的代谢化合物，例如脂溶性维生素和激素，在水溶液中的溶解度很低。很多技术被用于提高这些化合物在组织培养物、细胞培养物或其他水基应用中的溶解度。

Global Trade Item Number

SKUGTIN
C4767-25G04061835556038
C4767-100G04061835556021
C4767-500G04061833492734

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