C4866
Cardiogenol C hydrochloride
≥97% (HPLC), solid
Synonym(s):
4-(2-Hydroxyethylamino)-2-(4-methoxyphenylamino)-pyrimidine hydrochloride
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About This Item
Empirical Formula (Hill Notation):
C13H16N4O2 ·HCl
CAS Number:
Molecular Weight:
296.75
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
51111800
MDL number:
InChI
1S/C13H16N4O2.ClH/c1-19-11-4-2-10(3-5-11)16-13-15-7-6-12(17-13)14-8-9-18;/h2-7,18H,8-9H2,1H3,(H2,14,15,16,17);1H
SMILES string
Cl[H].COc1ccc(Nc2nccc(NCCO)n2)cc1
InChI key
QQAHYSZVJLHCNA-UHFFFAOYSA-N
assay
≥97% (HPLC)
form
solid
mol wt
296.75
packaging
pkg of 5 mg
solubility
H2O: soluble 10 mg/mL
storage temp.
−20°C
Biochem/physiol Actions
Cardiogenol C hydrochloride is a cardiomyogenesis inducer in embryonic stem cells.
Storage Class
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Xu Wu et al.
Journal of the American Chemical Society, 126(6), 1590-1591 (2004-02-12)
A phenotypic cell-based screen of a large combinatorial chemical library led to the identification of a class of diaminopyrimidine compounds (cardiogenol A-D) which can selectively and efficiently induce mouse embryonic stem cells (ESCs) to differentiate into cardiomyocytes. ESC-derived cardiomyocytes were
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