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C5132

Sigma-Aldrich

Carbazole

≥95% (GC)

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Synonym(s):
Dibenzopyrrole; Diphenylenimine
Empirical Formula (Hill Notation):
C12H9N
CAS Number:
86-74-8
Molecular Weight:
167.21
Beilstein:
3956
EC Number:
201-696-0
MDL number:
MFCD00004960
PubChem Substance ID:
24892756
NACRES:
NA.47

vapor pressure

400 mmHg ( 323 °C)

Quality Level

200

Assay

≥95% (GC)

form

powder

color

white to tan

bp

355 °C (lit.)

mp

243-246 °C (lit.)

solubility

acetone: 50 mg/mL

density

1.1 g/cm3 at 18 °C

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

c1ccc2c(c1)[nH]c3ccccc23

InChI

1S/C12H9N/c1-3-7-11-9(5-1)10-6-2-4-8-12(10)13-11/h1-8,13H

InChI key

UJOBWOGCFQCDNV-UHFFFAOYSA-N

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General description

Carbazole is an aromatic heterocyclic organic molecule.

Application

Carbazole has been used in the uronic acid assay.

Biochem/physiol Actions

Carbazole mainly interacts with DNA and damages it. These events suppress the synthesis of new DNA or RNA. Carbazole derivatives are involved in antimicrobial, antitumor, antiepileptic, antihistaminic, antioxidant, anti-inflammatory, antidiarrhoeal, analgesic, neuroprotective, and pancreatic lipase suppression activities.

Quality

May contain dark particles.

Pictograms

Health hazard
GHS08

Signal Word

Warning

Hazard Statements

H341 - H351 - H413

Hazard Classifications

Aquatic Chronic 4 - Carc. 2 - Muta. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

428.0 °F - closed cup

Flash Point(C)

220.0 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

危险化学品

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A complete set of hyaluronan fragments obtained from hydrolysis catalyzed by hyaluronidase: Application to studies of hyaluronan mass distribution by simple HPLC devices.
Tranchepain F, et al.
Analytical Biochemistry, 348, 232-242 (2006)
CARBAZOLE DERIVATIVES IN CANCER TREATMENT-A REVIEW.
Kanneti Naga M, et al.
World Journal of Pharmacy and Pharmaceutical Sciences (2015)
Isis E Mejías Carpio et al.
Nanoscale, 4(15), 4746-4756 (2012-07-04)
It is critical to develop highly effective antimicrobial agents that are not harmful to humans and do not present adverse effects on the environment. Although antimicrobial studies of graphene-based nanomaterials are still quite limited, some researchers have paid particular attention
Jong-Kwan Bin et al.
Advanced materials (Deerfield Beach, Fla.), 24(21), 2911-2915 (2012-05-03)
A new carbazole derivative with two carbazole moieties on the C3 and C6 positions of carbazole and triphenylsilane directly linked to the N of carbazole is successfully used as a highly efficient blue phosphorescent host in an organic light-emitting diode
Shen H Tan et al.
Organic letters, 14(22), 5621-5623 (2012-10-31)
The racemic modification of the Aspidosperma alkaloid limaspermidine (1) has been prepared in ten steps including one involving a Raney-cobalt-mediated tandem reductive cyclization of nitrile 8 to give the tetracyclic system 9b. Compound (±)-1 has been converted over two steps
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