Skip to Content
Merck
CN

Key Documents

View All Documentation

C5145

Chlormadinone acetate

≥98%

Synonym(s):

17α-Acetoxy-6-chloro-4,6-pregnadiene-3,20-dione, 6-Chloro-17α-hydroxy-4,6-pregnadiene-3,20-dione 17-acetate, 6-Chloro-6-dehydro-17α-acetoxyprogesterone, Gestafortin, Matrol, Menstridyl

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):
C23H29ClO4
CAS Number:
302-22-7
Molecular Weight:
404.93
UNSPSC Code:
41116107
NACRES:
NA.77
PubChem Substance ID:
24892757
EC Number:
206-118-0
Beilstein/REAXYS Number:
2633614
MDL number:
MFCD00056471
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

assay

≥98%

form

powder

SMILES string

[H][C@]12CC[C@@]3(C)[C@@]([H])(CC[C@]3(OC(C)=O)C(C)=O)[C@]1([H])C=C(Cl)C4=CC(=O)CC[C@]24C

InChI

1S/C23H29ClO4/c1-13(25)23(28-14(2)26)10-7-18-16-12-20(24)19-11-15(27)5-8-21(19,3)17(16)6-9-22(18,23)4/h11-12,16-18H,5-10H2,1-4H3/t16-,17+,18+,21-,22+,23+/m1/s1

InChI key

QMBJSIBWORFWQT-DFXBJWIESA-N

Gene Information

human ... PGR(5241)

Looking for similar products? Visit Product Comparison Guide

Biochem/physiol Actions

Review of progestogenic and related pharmacological effects of chlormadinone acetate.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

Regulatory Information

涉药品监管产品

This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCBZ5030
BCBN8070V
BCBN8070
BCBL5397V
BCBL5397

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Ting Huang et al.
Die Pharmazie, 66(3), 212-215 (2011-05-11)
Chlormadinone acetate (CMA), a derivative of 17-a-hydroxyprogesterone, has been widely used as an orally effective progestogen in hormone replacement therapy (HRT). Glucuronidation catalyzed by UDP-glucuronosyltransferases (UGTs) is one of the major steps responsible for the metabolism of many drugs, environmental
Nathalie Chabbert-Buffet et al.
Contraception, 83(3), 229-237 (2011-02-12)
Systemic lupus erythematosus (SLE) affects women of child-bearing age. Combined oral contraceptives can worsen the course and increase the risk of thrombosis. The objectives of this study were to provide an alternative contraception and thus evaluate the gynecological tolerability of
Maurizio Guido et al.
Reproductive sciences (Thousand Oaks, Calif.), 17(8), 767-775 (2010-07-03)
This is the first study evaluating the clinical, metabolic, and hormonal effects of the ethinylestradiol-chlormadinone acetate (EECMA) combination in hirsute women with polycystic ovary syndrome (PCOS). Ultrasonographic pelvic examination, hirsutism score, and hormone profile evaluation were performed at baseline and
Gunther Göretzlehner et al.
Clinical drug investigation, 31(4), 269-277 (2011-01-22)
The prescribing of extended regimens of oral contraceptives (OCs) is increasing in routine gynaecological practice as a means of reducing the number of annual menstrual bleeds. Typically, this involves taking one pill per day for, say, 84 days continuously (4×21
R Hermes et al.
Theriogenology, 78(6), 1217-1223 (2012-08-18)
The estrous cycle length in the white rhinoceros (Ceratotherium simum) is either 4 or 10 wk. The cause(s) for this variation as well as the poor fertility rate in captivity remains under debate in this species. Most captive adult white
View All Related Papers

Global Trade Item Number

SKUGTIN
C5145-1G04061833501818

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service