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Merck
CN

C5374

CB-DMB

≥98% (HPLC)

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About This Item

Empirical Formula (Hill Notation):
C22H23Cl2N7O
CAS Number:
Molecular Weight:
472.37
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
solid
Quality level:
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InChI

1S/C22H23Cl2N7O/c1-12-3-6-15(13(2)9-12)11-28-22(26)31-21(32)17-19(25)30-20(18(24)29-17)27-10-14-4-7-16(23)8-5-14/h3-9H,10-11H2,1-2H3,(H3,25,27,30)(H3,26,28,31,32)

SMILES string

Cc1ccc(CNC(=N)NC(=O)c2nc(Cl)c(NCc3ccc(Cl)cc3)nc2N)c(C)c1

InChI key

MGLQFHOCPGELNL-UHFFFAOYSA-N

assay

≥98% (HPLC)

form

solid

solubility

DMSO: 20 mg/mL

storage temp.

2-8°C

Quality Level

Biochem/physiol Actions

CB-DMB is a specific and potent inhibitor of the Na+-Ca2+exchanger (NCX).
CB-DMB is a specific and potent inhibitor of the Na+-Ca2+exchanger (NCX); pan-inhibitor of the NA+-Ca2+exchanger isoforms.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Voltage-gated sodium channels are present in most excitable cell membranes and play an important role in generating action potentials.

电压门控钠通道存在于大多数可兴奋细胞膜中,在产生动作电位方面起着重要作用。

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