C5762
Colominic acid sodium salt from Escherichia coli
Synonym(s):
Poly[2,8-(N-acetylneuraminic acid sodium salt)]
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About This Item
Linear Formula:
(C11H16NNaO8)n
CAS Number:
NACRES:
NA.76
UNSPSC Code:
51102829
MDL number:
form
powder
Quality Level
solubility
H2O: 50 mg/mL
antibiotic activity spectrum
viruses
mode of action
enzyme | inhibits
storage temp.
−20°C
InChI
1S/C11H20NO7.3Na/c1-6(15)12-10-7(16)4-9(18-3-2-13)19-11(10)8(17)5-14;;;/h3,7-11,13-14,16-17H,2,4-5H2,1H3,(H,12,15);;;/q;3*+1
InChI key
IPYNPWIUCZLARC-UHFFFAOYSA-N
Application
Colominic acid is used to study protein polysialylation processes. It is a substrate for CMP-NeuAc:(NeuAcα2→8)n (colominic acid) sialyltransferase.
Other Notes
Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Articles
Understand sialic acid structure, function, signaling, and modifications. Easily find products for sialic acid research.
J Finne et al.
Journal of immunology (Baltimore, Md. : 1950), 138(12), 4402-4407 (1987-06-15)
The structurally similar polysialic acid capsules of group B meningococci and Escherichia coli K1 are poor immunogens, and attempts are currently being made to improve their immunogenicity by chemical modifications. An IgG monoclonal antibody to these polysialic acid capsules was
J Roth et al.
Proceedings of the National Academy of Sciences of the United States of America, 85(9), 2999-3003 (1988-05-01)
A unique structural feature of the neural cell adhesion molecule N-CAM is the presence of homopolymers of alpha (2----8)-linked sialic acid units. We have used two specific probes for the detection of poly(sialic acid) in normal human kidney and Wilms
J Roth et al.
Proceedings of the National Academy of Sciences of the United States of America, 84(7), 1969-1973 (1987-04-01)
We report the presence of alpha(2----8)-linked polysialic acid as detected with a monoclonal antibody outside the nervous tissue in the postnatal developing rat kidney. By immunoblot analysis, the reactivity was confined to a broad band of apparent molecular mass 200-250
Global Trade Item Number
| SKU | GTIN |
|---|---|
| C5762-1G | 04061833502471 |
| C5762-100MG | 04061833270028 |