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C6003

Chlorophyllin sodium copper salt

Name: Chlorophyllin sodium copper salt
Brand: SIGMA

commercial grade, powder

Synonym(s):

Chlorophyllin, coppered trisodium salt

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About This Item

Empirical Formula (Hill Notation):

C₃₄H₃₁CuN₄Na₃O₆

CAS Number:

11006-34-1

Molecular Weight:

724.15

MDL number:

MFCD28016032

UNSPSC Code:

12171500

PubChem Substance ID:

24892826

NACRES:

NA.47

EC Number:

234-242-5

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Product Name

Chlorophyllin sodium copper salt,

form

powder

Quality Level

200

technique(s)

microbe id | staining: suitable

color

black, green to very dark green

solubility

H₂O: 100 mg/mL, dark green

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

2-8°C

SMILES string

[Na+].[Na+].[Na+].CCc1c(C)c2cc3c(C=C)c(C)c4cc5nc(C(CCC([O-])=O)C5C)c(CC([O-])=O)c6c(C([O-])=O)c(C)c(cc1n2)n6[Cu]n34

InChI

1S/C34H36N4O6.Cu.3Na/c1-7-19-15(3)23-12-25-17(5)21(9-10-29(39)40)32(37-25)22(11-30(41)42)33-31(34(43)44)18(6)26(38-33)14-28-20(8-2)16(4)24(36-28)13-27(19)35-23;;;;/h7,12-14,17,21H,1,8-11H2,2-6H3,(H5,35,36,37,38,39,40,41,42,43,44);;;;/q;+2;3*+1/p-5

InChI key

HWDGVJUIHRPKFR-UHFFFAOYSA-I

Related Categories

Clinical & Diagnostics

Hematology Stains

Histology Stains

Tissue Diagnostics

Application

Chlorophyllin sodium copper salt has been used to study the effect of chlorophyllin against radiation-induced hematopoietic syndrome. It has been used to study the effect of chlorophyllin on the excretion of PhIP (2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine) and its metabolites into the breast-milk of lactating rats.

Biochem/physiol Actions

Chlorophyllin is a water soluble derivative of chlorophyll. It has chemopreventive properties and forms a non-covalent complex with many mutagenic/carcinogenic molecules. The complex formation reduces absorption or allows excretion of the mutagenic/carcinogenic molecules. Chlorophyllin also exhibits antioxidant, antiapoptotic and immunostimulatory effects. It provides benefits, such as prevention of body odor and increased wound healing.

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Amelioration of radiation-induced hematopoietic syndrome by an antioxidant chlorophyllin through increased stem cell activity and modulation of hematopoiesis.

Suryavanshi S, et al.

Free Radical Biology & Medicine, 85, 56-70 (2015)

Spectroscopic studies on interaction and sonodynamic damage of metallochlorophyllin (Chl-M (M=Fe, Zn and Cu)) to protein under ultrasonic irradiation.

Jingqun Gao et al.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 79(5), 849-857 (2011-06-18)

In this paper, the chlorophyll derivatives, metallochlorophyllin (Chl-M) (M=Fe, Zn and Cu) including chlorophyllin iron (Chl-Fe), chlorophyllin zinc (Chl-Zn) and chlorophyllin copper (Chl-Cu), were adopted as sonosensitizers to combine with ultrasonic irradiation, and the sonodynamic damage of bovine serum albumin

Inhibition of fried meat-induced colorectal DNA damage and altered systemic genotoxicity in humans by crucifera, chlorophyllin, and yogurt.

Daniel T Shaughnessy et al.

PloS one, 6(4), e18707-e18707 (2011-05-05)

Dietary exposures implicated as reducing or causing risk for colorectal cancer may reduce or cause DNA damage in colon tissue; however, no one has assessed this hypothesis directly in humans. Thus, we enrolled 16 healthy volunteers in a 4-week controlled

Anticarcinogenic effect of probiotic fermented milk and chlorophyllin on aflatoxin-B₁-induced liver carcinogenesis in rats.

M Kumar et al.

The British journal of nutrition, 107(7), 1006-1016 (2011-08-06)

The present investigation was carried out to evaluate the hepatoprotective effect of probiotic fermented milk (FM) containing Lactobacillus rhamnosus GG and Lactobacillus casei strain Shirota, alone as well as in combination with chlorophyllin (CHL) as an antioxidant agent in male

A comparative study of the anticlastogenic effects of chlorophyllin on N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) or 7,12-dimethylbenz (α) anthracene (DMBA) induced micronuclei in mammalian cells in vitro and in vivo.

Maria Rosaria Grossi et al.

Toxicology letters, 214(3), 235-242 (2012-09-19)

Chlorophyllin (CHL), a water soluble derivative of chlorophyll has been shown to have both anticarcinogenic and antigenotoxic properties. We evaluated the protective effects of CHL (25μM in vitro, 4 and 100mg/kg. b.w.) on the clastogenic action of two model carcinogens

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Global Trade Item Number

SKU	GTIN
C6003-5G	04061832342085
C6003-25G	04061833502976
C6003-100G	04061833502969

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