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Merck
CN

C6206

N-Carboxymethyl-6-(2,2-dicyanovinyl)-1,2,3,4-tetrahydroquinoline

≥98% purity (HPLC), powder

Synonym(s):

CDCQ

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About This Item

Empirical Formula (Hill Notation):
C15H13N3O2
CAS Number:
Molecular Weight:
267.28
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47
MDL number:
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Product Name

N-Carboxymethyl-6-(2,2-dicyanovinyl)-1,2,3,4-tetrahydroquinoline, ≥98% (HPLC)

SMILES string

OC(=O)CN1CCCc2cc(ccc12)\C=C(\C#N)C#N

InChI key

LSKCTKMTYNICJW-UHFFFAOYSA-N

InChI

1S/C15H13N3O2/c16-8-12(9-17)6-11-3-4-14-13(7-11)2-1-5-18(14)10-15(19)20/h3-4,6-7H,1-2,5,10H2,(H,19,20)

assay

≥98% (HPLC)

form

powder

color

yellow

solubility

DMSO: 17.5 mg/mL, clear, bright yellow

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

2-8°C

Quality Level

Other Notes

Fluorescent molecular rotor

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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T Iio et al.
Journal of biochemistry, 113(2), 196-199 (1993-02-01)
1-(2-Hydroxyethyl)-6-[(2,2-dicyano)vinyl]-2,3,4-trihydroquinoli ne (DCQ) is a fluorescent dye and its fluorescence yield is determined by a freedom of intramolecular rotation. When DCQ was added to an actin solution, its fluorescence intensity increased as the actin molecule transformed from G-actin to F-actin.
T Iwaki et al.
Biochemistry, 32(29), 7589-7592 (1993-07-27)
We have prepared monoclonal antibodies for the fluorescent molecular rotors 9-(2-carboxy-2-cyanovinyl)julolidine (CCVJ) and 9-(dicyanovinyl)julolidine (DCVJ). Mouse monoclonal antibody (IgG2b) prepared against CCVJ-conjugated bovine serum albumin strongly bound CCVJ and DCVJ. The CCVJ (or DCVJ) binding to IgG and Fab was

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