biological source
plant (Croton tiglium L)
form
viscous liquid
density
0.94 g/mL at 25 °C (lit.)
functional group
ester
lipid type
oils
shipped in
ambient
storage temp.
room temp
Quality Level
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General description
Croton oil is a toxic viscous liquid extracted from seeds of Croton tiglium. It is pale yellow to brown in color and is transparent in nature. Croton oil has a strong irritant property and is used along with phenol in some chemical peels. It also has a tumor promoting ability.
Croton oil is extracted from Croton tiglium L. It consists of crotonoleic acid, crotonic acid, crotonyl alcohol, crotonyl alcohol bisester and crotonyl alcohol trisester. Croton oil acts as a stimulant in the skin and mucosal inflammation. It is associated with allergic contact dermatitis (ACD) and skin carcinoma. Croton oil functions as a skin peeling agent.
Application
Croton oil has been used to induce acute skin inflammation.
Croton oil has been used to induce inflammation in mouse ears.
Other Notes
Essential oil rich in glycerides of saturated fatty acids, and in phorbol esters.
Storage Class
10 - Combustible liquids
wgk
WGK 3
flash_point_f
165.2 °F - closed cup
flash_point_c
74 °C - closed cup
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
Regulatory Information
监管及禁止进口产品
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Thekkuttuparambil Ananthanarayanan Ajith et al.
Journal of experimental therapeutics & oncology, 9(3), 207-215 (2011-11-11)
The roles of 7,12-dimethylbenz[a]anthracene (DMBA), a polycyclic aromatic hydrocarbon (PAH), and 12-O-tetradecanoylphorbol-13-acetate (TPA) a skin tumor promoter present in croton oil, are clearly implicated in the formation of skin papilloma. The effect of ethyl acetate extract of Phellinus rimosus, a
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Iranian biomedical journal, 16(2), 59-67 (2012-07-18)
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Direct effect of croton oil on intestinal epithelial cells and colonic smooth muscle cells
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