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Merck
CN

C6719

Croton oil

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About This Item

CAS Number:
UNSPSC Code:
12352211
NACRES:
NA.25
MDL number:
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biological source

plant (Croton tiglium L)

form

viscous liquid

density

0.94 g/mL at 25 °C (lit.)

functional group

ester

lipid type

oils

shipped in

ambient

storage temp.

room temp

Quality Level

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Application

Croton oil has been used to induce acute skin inflammation.
Croton oil has been used to induce inflammation in mouse ears.

General description

Croton oil is a toxic viscous liquid extracted from seeds of Croton tiglium. It is pale yellow to brown in color and is transparent in nature. Croton oil has a strong irritant property and is used along with phenol in some chemical peels. It also has a tumor promoting ability.
Croton oil is extracted from Croton tiglium L. It consists of crotonoleic acid, crotonic acid, crotonyl alcohol, crotonyl alcohol bisester and crotonyl alcohol trisester. Croton oil acts as a stimulant in the skin and mucosal inflammation. It is associated with allergic contact dermatitis (ACD) and skin carcinoma. Croton oil functions as a skin peeling agent.

Other Notes

Essential oil rich in glycerides of saturated fatty acids, and in phorbol esters.

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

165.2 °F - closed cup

flash_point_c

74 °C - closed cup

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Regulatory Information

监管及禁止进口产品
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Bang-Tian Chen et al.
Oxidative medicine and cellular longevity, 2012, 537923-537923 (2012-08-18)
While beneficial health properties of tea leaves have been extensively studied, less attention is paid to the flowers of tea. In this study, the anti-inflammatory effects of hot water extract of tea (Camellia sinensis) flowers were investigated. Pharmacological studies found
Effects of Haruan (Channa striatus) Based Cream on Acute Inflammation in Croton Oil Induced Mice Ear Edema Model
Abedi S, et al.
Research Journal of Biological Sciences, 7(4), 181-187 (2012)
Gabriella Coruzzi et al.
Experimental dermatology, 21(1), 32-37 (2011-12-14)
The effects of the histamine H(4) receptor antagonist JNJ7777120 were evaluated in a model of acute skin inflammation induced by local application of croton oil. The influence of strain on the effect of JNJ7777120 was investigated in four different mouse
An examination of the phenol-croton oil peel: Part I. Dissecting the formula
Hetter GP
Plastic and Reconstructive Surgery, 105(1), 227-239 (2000)
Sulaiman Hamizah et al.
Asian Pacific journal of cancer prevention : APJCP, 13(6), 2533-2539 (2012-09-04)
Annona muricata L (Annonaceae), commonly known as soursop has a long, rich history in herbal medicine with a lengthy recorded indigenous use. It had also been found to be a promising new anti-tumor agent in numerous in vitro studies. The

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