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Merck
CN

C7401

Anti-Lectin, Canavalia ensiformis antibody produced in rabbit

fractionated antiserum, lyophilized powder

Synonym(s):

Anti-Con A, Anti-Jack Bean Concanavalin A

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.46
MDL number:
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Product Name

Anti-Lectin, Canavalia ensiformis antibody produced in rabbit, fractionated antiserum, lyophilized powder

biological source

rabbit

conjugate

unconjugated

antibody form

fractionated antiserum

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

Canavalia ensiformis

packaging

vial of ~2 mL lyophilized antiserum

technique(s)

indirect ELISA: 1:25,000

storage temp.

2-8°C

target post-translational modification

unmodified

Quality Level

Application

Anti-Lectin, Canavalia ensiformis antibody produced in rabbit has been used in:
  • enzyme-linked immunosorbent assays (ELISA)
  • immunochemistry
  • enhanced chemiluminescence ECL western blot analysis
  • western blot

Biochem/physiol Actions

Concanavalin A is a lectin isolated from Canavalia ensiformis or Jack bean seeds. It has potent mitogenic effect on T cells and triggers the activity of both helper and suppressor T cells exhibiting immune regulator activity. Con A triggers autophagy by binding on the cell membrane glycoprotein and is internalized to the mitochondria. It activates immune response in liver and displays anti-hepatoma effect.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Lectins are highly specific carbohydrate binding proteins useful in carbohydrate and cell membrane studies, as well as cell agglutination and typing techniques.

Immunogen

Jack Bean Concanavalin A (Con A).

Physical form

Lyophilized from 0.01 M phosphate buffered saline, pH 7.2.

Preparation Note

Prior to reconstitution store the product at 2-8 °C. After reconstitution, the solution may be stored frozen in working aliquots. Repeated freezing and thawing is not recommended. If slight turbidity occurs upon prolonged storage clarify the solution by centrifugation before use.
Reconstitute with 2 mL deionized water.

Legal Information

ECL is a trademark of Cytiva

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

常规特殊物品
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The use of concanavalin A to study the immunoregulation of human T cells.
J M Dwyer et al.
Clinical and experimental immunology, 46(2), 237-249 (1981-11-01)
B Fairburn et al.
Biochimie, 88(9), 1165-1174 (2006-05-13)
The stress protein gp96 exhibits a number of immunological activities, the majority of studies into which have used gp96 purified from a variety of tissues. On the basis of 1-D gel electrophoresis, the purity of these preparations has been reported
Nicolas Sauvion et al.
Journal of insect physiology, 50(12), 1137-1150 (2005-01-27)
Concanavalin A (lectin from Canavalia ensiformis L., ConA) has previously been shown to act as a feeding inhibitor for Acyrthosiphon pisum, the pea aphid. In the present study a range of histochemical and biochemical techniques were used to elucidate the
Rong Wang et al.
Cell death & disease, 13(7), 626-626 (2022-07-20)
Castration-resistance of prostate cancer is one of the most challenging clinical problems. In the present study, we have performed proteomics and glycomics using LNCaP model. Growth differentiation factor-15 (GDF15) level is increased in androgen receptor (AR) inhibitor-resistant cells and the
Hai-Xia Wang et al.
World journal of gastroenterology, 18(2), 119-125 (2012-01-19)
As a chronic inflammatory disease of the liver, the pathogenic mechanisms of autoimmune hepatitis (AIH) have not yet been elucidated, with prognosis and diagnosis remaining unsatisfied. Currently the only viable treatments of AIH are immunosuppressant application and liver transplantation. It

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