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C7515

Cannabidiol

Name: Cannabidiol
Brand: SIGMA

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About This Item

Empirical Formula (Hill Notation):

C₂₁H₃₀O₂

CAS Number:

13956-29-1

Molecular Weight:

314.46

UNSPSC Code:

12352200

MDL number:

MFCD04221141

Form:

powder

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form

powder

drug control

USDEA Schedule I; regulated under CDSA - not available from Sigma-Aldrich Canada

storage temp.

2-8°C

SMILES string

Oc1c(c(cc(c1)CCCCC)O)C2[C@@H](CCC(=C2)C)C(=C)C

InChI

1S/C21H30O2/c1-5-6-7-8-16-12-19(22)21(20(23)13-16)18-11-15(4)9-10-17(18)14(2)3/h11-13,17-18,22-23H,2,5-10H2,1,3-4H3/t17-,18?/m0/s1

InChI key

QHMBSVQNZZTUGM-ZENAZSQFSA-N

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Related Categories

Bioactive Small Molecule Inhibitors

Cannabis Testing Products: Cultivator Solutions

Biochem/physiol Actions

Not psychoactive in humans.

Other Notes

Major component of marijuana from C. sativa

pictograms

GHS08,GHS07

signalword

Warning

hcodes

H302,H361d

pcodes

P202 - P264 - P280 - P301 + P312 - P308 + P313 - P405

Hazard Classifications

Acute Tox. 4 Oral - Repr. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Involvement of serotonin-mediated neurotransmission in the dorsal periaqueductal gray matter on cannabidiol chronic effects in panic-like responses in rats.

Alline Cristina Campos et al.

Psychopharmacology, 226(1), 13-24 (2012-09-26)

Cannabidiol (CBD) is a non-psychotomimetic constituent of Cannabis sativa plant that promotes antianxiety and anti-panic effects in animal models after acute systemic or intra-dorsal periaqueductal gray (DPAG) administration. However, the effects of CBD repeated administration, and the possible mechanisms involved

Nasal administration of drugs as a new non-invasive strategy for efficient treatment of multiple sclerosis.

Shaher Duchi et al.

Journal of neuroimmunology, 258(1-2), 32-40 (2013-03-23)

We investigated the efficiency of nasal drug administration as a new non-invasive treatment strategy for MS. Glatiramer Acetate (GA) and GA-Cannabidiol (CBD) combination administered in nasal delivery system (NDS) resulted in a statistically significant decrease of clinical scores and inflammatory

Cannabinoid- and lysophosphatidylinositol-sensitive receptor GPR55 boosts neurotransmitter release at central synapses.

Sergiy Sylantyev et al.

Proceedings of the National Academy of Sciences of the United States of America, 110(13), 5193-5198 (2013-03-09)

G protein-coupled receptor (GPR) 55 is sensitive to certain cannabinoids, it is expressed in the brain and, in cell cultures, it triggers mobilization of intracellular Ca(2+). However, the adaptive neurobiological significance of GPR55 remains unknown. Here, we use acute hippocampal

Cannabidiol reduces host immune response and prevents cognitive impairments in Wistar rats submitted to pneumococcal meningitis.

Tatiana Barichello et al.

European journal of pharmacology, 697(1-3), 158-164 (2012-10-23)

Pneumococcal meningitis is a life-threatening disease characterized by an acute infection affecting the pia matter, arachnoid and subarachnoid space. The intense inflammatory response is associated with a significant mortality rate and neurologic sequelae, such as, seizures, sensory-motor deficits and impairment

Effects of acute systemic administration of cannabidiol on sleep-wake cycle in rats.

Marcos Hortes N Chagas et al.

Journal of psychopharmacology (Oxford, England), 27(3), 312-316 (2013-01-25)

Cannabidiol (CBD) is one of the main components of Cannabis sativa and has a wide spectrum of action, including effects in the sleep-wake cycle. The objective of this paper is to assess the effects on sleep of acute systemic administration

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Global Trade Item Number

SKU	GTIN
C7515-100MG	04061832283869
C7515-1G	04061822372917

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