C7670
D-Cycloserine
powder
Synonym(s):
(R)-4-Amino-3-isoxazolidone, 4-Amino-3-isoxazolidinone
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About This Item
Empirical Formula (Hill Notation):
C3H6N2O2
CAS Number:
Molecular Weight:
102.09
EC Number:
200-688-4
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
80798
MDL number:
sterility
γ-irradiated
form
powder
mp
147 °C (dec.) (lit.)
solubility
0.1 M phosphate pH 8.0: 10 mg/mL (as a stock solution)
antibiotic activity spectrum
Gram-negative bacteria, Gram-positive bacteria, mycobacteria
mode of action
cell wall synthesis | interferes
storage temp.
2-8°C
SMILES string
N[C@@H]1CONC1=O
InChI
1S/C3H6N2O2/c4-2-1-7-5-3(2)6/h2H,1,4H2,(H,5,6)/t2-/m1/s1
InChI key
DYDCUQKUCUHJBH-UWTATZPHSA-N
General description
Chemical structure: amino acid derivatives
Application
Recommended for use in molecular biology applications at 100-200 μg/ml.
Biochem/physiol Actions
Mode of Action: Inhibits cell wall biosynthesis (D-Ala peptide bond formation). Also prevents conversion of D-Ala to L-Ala. Bacteriostatic.
Partial agonist at the glycine modulatory site of NMDA glutamatergic receptors; antibiotic against Gram-negative bacteria.
Mode of Resistance: D-Ala transport interference.
Partial agonist at the glycine modulatory site of NMDA glutamatergic receptors; antibiotic against Gram-negative bacteria.
Mode of Resistance: D-Ala transport interference.
Preparation Note
Prepare stock solutions directly in the vial at any concentration in the recommended range. Unstable in solution; prepare immediately before use.
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Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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