C8230
Dihydroceramide C6
solid
Synonym(s):
N-Hexanoyldihydrosphingosine
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About This Item
Empirical Formula (Hill Notation):
C24H49NO3
Molecular Weight:
399.65
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352211
MDL number:
InChI
1S/C24H49NO3/c1-3-5-7-8-9-10-11-12-13-14-15-16-18-19-23(27)22(21-26)25-24(28)20-17-6-4-2/h22-23,26-27H,3-21H2,1-2H3,(H,25,28)/t22-,23+/m0/s1
SMILES string
OC[C@]([H])(NC(CCCCC)=O)[C@]([H])(O)CCCCCCCCCCCCCCC
InChI key
VUMHYWBWYSPQMM-XZOQPEGZSA-N
form
solid
color
white
solubility
DMF: soluble, DMSO: soluble, ethanol: soluble
storage temp.
−20°C
Quality Level
Biochem/physiol Actions
Inactive form of C6 ceramide for use as a negative control.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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K Kitatani et al.
Archives of biochemistry and biophysics, 382(2), 296-302 (2000-11-09)
The effect of ceramide on Ca2+-dependent translocation of cytosolic phospholipase A2 (cPLA2) to membranes was studied. Pretreatment of platelets with sphingomyelinase or C6-ceramide (N-hexanoylsphingosine) led to apparent enhancement of Ca2+-ionophore A23187-stimulated arachidonic acid release but did not affect the cytosolic
F J Sánchez-Gómez et al.
Allergy, 72(3), 385-396 (2016-06-21)
Allergic reactions to β-lactams are among the most frequent causes of drug allergy and constitute an important clinical problem. Drug covalent binding to endogenous proteins (haptenation) is thought to be required for activation of the immune system. Nevertheless, neither the
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