C8284
Anti-C-Reactive Protein antibody produced in goat
whole antiserum
Synonym(s):
Anti-CRP
Product Name
Anti-C-Reactive Protein antibody produced in goat, whole antiserum
biological source
goat
conjugate
unconjugated
antibody form
whole antiserum
antibody product type
primary antibodies
clone
polyclonal
contains
15 mM sodium azide
species reactivity
human
technique(s)
Ouchterlony double diffusion: 1:16-1:32
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... CRP(1401)
Application
Anti-C-Reactive Protein antibody produced in goat has been used in enzyme-linked immunosorbent assay (ELISA). It has also been used in immunoassay reproducibility and binding affinity investigation of CRP-anti-CRP interaction.
Anti-C-Reactive protein antibody has been used in:
- immunoassay reproducibility and binding affinity investigation of CRP-anti-CRP interaction.
- in-house ELISA assay to study the CRP levels in plasma sample.
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Enzyme-linked immunosorbent assay (1 paper)
Enzyme-linked immunosorbent assay (1 paper)
Biochem/physiol Actions
C-reactive protein (CRP) plays an important role to provide an enhanced clearance of inappropriate materials from the plasma, whether these are of extrinsic origin, such as microorganisms and their products or the autologous products of cell damage and death. It acts as a systemic biomarker of acute inflammation and tissue damage.
Specificity for human CRP is determined by immunoelectrophoresis (IEP) versus human CRP positive serum and purified human CRP. No reactivity with normal human serum is observed.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
C-reactive protein (CRP) is a first acute-phase plasma protein. It is synthesized in the hepatocyte and the concentration increase during inflammatory states even chronic inflammation. It′s level can increase during inflammation by up to 100 or 500 times.
C-reactive protein is encoded by the gene mapped to human chromosome 1q23.2.
Physical form
Goat Anti-Human CRP is supplied as a liquid containing 0.1% sodium azide (see MSDS) as preservative.
Preparation Note
For continuous use, store at 2-8 °C for up to one month. For extended storage, the solution may be frozen in working aliquots. Repeated freezing and thawing is not recommended. Storage in "frost-free" freezers not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use.
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Storage Class
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
常规特殊物品
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Intestinal parasites coinfection does not alter plasma cytokines profile elicited in acute malaria in subjects from endemic area of Brazil
Sanchez-AJC, et al.
Mediators of Inflammation (2014)
Chih-Shen Chuang et al.
Scientific reports, 9(1), 17131-17131 (2019-11-22)
In this study, we developed a portable smartphone-based diffusometry for analyzing the C-reactive protein (CRP) concentration. An optimized fluorescence microscopic add-on system for a smartphone was used to image the 300 nm fluorescent beads. Sequential nanobead images were recorded for a
J Hurlimann et al.
The Journal of experimental medicine, 123(2), 365-378 (1966-02-01)
The site of formation of C-reactive protein (CxRP, CRP) has been studied with tissues from rabbits, monkeys, and human beings. Rabbits and monkeys were stimulated to produce the acute phase protein by injection of turpentine, croton oil, endotoxin, paratyphoid-typhoid vaccine
M B Pepys et al.
Advances in immunology, 34, 141-212 (1983-01-01)
The acute phase response among plasma proteins is a normal response to tissue injury and is therefore a fundamental aspect of many diverse disease processes. It probably usually has a beneficial net function in limiting damage and promoting repair but
C-reactive protein: a critical update.
Mark B Pepys et al.
The Journal of clinical investigation, 111(12), 1805-1812 (2003-06-19)
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Datasheet
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