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Merck
CN

C8355

D-erythro-Ceramide C8 1-phosphate

≥93% (HPLC), powder or solid

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About This Item

Empirical Formula (Hill Notation):
C26H52NO6P
Molecular Weight:
505.67
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352211
MDL number:
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Product Name

D-erythro-Ceramide C8 1-phosphate, ≥93% (HPLC), powder or solid

InChI

1S/C26H52NO6P/c1-3-5-7-9-10-11-12-13-14-15-16-18-19-21-25(28)24(23-33-34(30,31)32)27-26(29)22-20-17-8-6-4-2/h19,21,24-25,28H,3-18,20,22-23H2,1-2H3,(H,27,29)(H2,30,31,32)/b21-19+/t24-,25+/m0/s1

SMILES string

CCCCCCCCCCCCC\C=C\[C@@H](O)[C@H](COP(O)(O)=O)NC(=O)CCCCCCC

InChI key

VSSNYUXSRXINIP-WRBRXSDHSA-N

assay

≥93% (HPLC)

form

film
powder or solid

color

white to off-white

solubility

DMSO: 15 mg/mL
ethanol: 20 mg/mL, clear to hazy (Colorless to faint yellow)

storage temp.

−20°C

Quality Level

Biochem/physiol Actions

Cell permeable stimulator of DNA synthesis in cultured fibroblasts; antagonizes mitogenic activity.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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A Gomez-Muñoz et al.
Molecular pharmacology, 47(5), 833-839 (1995-05-01)
Ceramide and ceramide-1-phosphate are sphingolipid analogues of diacylglycerol and phosphatidate, respectively, and they are putative second messengers of agonist-stimulated sphingomyelin metabolism. The interactions of exogenous cell-permeable ceramides and ceramide-1-phosphates in modifying DNA synthesis and signal transduction were investigated in Rat-1

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