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Merck
CN

C8552

Cytidine 5′-triphosphate disodium solution

HPLC purified, aqueous solution for RNA polymerase transcription

Synonym(s):

CTP-Na2

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About This Item

Empirical Formula (Hill Notation):
C9H16N3O14P3Na2
CAS Number:
81012-87-5
Molecular Weight:
529.14
NACRES:
NA.52
PubChem Substance ID:
24893072
UNSPSC Code:
41106305
MDL number:
MFCD00078193
Form:
liquid
Storage temp.:
−20°C

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Product Name

Cytidine 5′-triphosphate disodium solution, HPLC purified, aqueous solution for RNA polymerase transcription

Quality Level

300

InChI

1S/C9H16N3O14P3.2Na/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H2,10,11,15)(H2,16,17,18);;/q;2*+1/p-2/t4-,6-,7-,8-;;/m1../s1

SMILES string

[Na+].[Na+].NC1=NC(=O)N(C=C1)[C@@H]2O[C@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]2O

InChI key

NFQMDTRPCFJJND-WFIJOQBCSA-L

form

liquid

concentration

95-105 mM in H2O (adjusted to pH 7 with Sodium Hydroxide)

color

colorless

foreign activity

DNase and RNase, none detected

shipped in

dry ice

storage temp.

−20°C

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Application

For use in DNA-dependent RNA polymerase transcription

General description

Cytidine 5′-triphosphate (CTP) is a high-energy molecule and pyrimidine nucleoside triphosphate. It acts as a substrate for the RNA synthesis. CTP also acts as a coenzyme during the synthesis of glycerophospholipids and glycosylation of proteins. It is made up of cytidine and three phosphate groups and can be a potent phosphate source.

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

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Certificates of Analysis (COA)

Lot/Batch Number
SLCJ9794
058K5058
129H5963
114K7047
103K7005

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Sambrook, J., et al.
Molecular Cloning: A Laboratory Manual, 5-5 (1989)
Microwave-assisted hydrothermal rapid synthesis of amorphous calcium phosphate nanoparticles and hydroxyapatite microspheres using cytidine 5'-triphosphate disodium salt as a phosphate source
Zhao J, et al.
Materials Letters, 124, 208-211 (2014)
Xi Liu et al.
Anti-cancer drugs, 25(6), 690-703 (2014-03-29)
Treatment of mammalian cells with chemotherapeutic drugs can result in perturbations of nucleotide pools. Monitoring these perturbations in cultured tumor cells from human sources is useful for assessment of the effect of drug therapy and a better understanding of the

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