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C9650

β-Cyano-L-alanine

Name: &#946;-Cyano-<SC>L</SC>-alanine
Brand: SIGMA

≥95%, suitable for ligand binding assays

Synonym(s):

3-cyano-L-alanine

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About This Item

Empirical Formula (Hill Notation):

C₄H₆N₂O₂

CAS Number:

6232-19-5

Molecular Weight:

114.10

UNSPSC Code:

12352209

PubChem Substance ID:

24893182

NACRES:

NA.26

MDL number:

MFCD00021722

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Properties

Product Name

β-Cyano-L-alanine, ≥95%

Quality Level

200

assay

≥95%

form

powder

technique(s)

ligand binding assay: suitable

color

white

mp

217 °C

storage temp.

−20°C

SMILES string

OC([C@@H](N)CC#N)=O

InChI

1S/C4H6N2O2/c5-2-1-3(6)4(7)8/h3H,1,6H2,(H,7,8)/t3-/m0/s1

InChI key

BXRLWGXPSRYJDZ-VKHMYHEASA-N

Description

Biochem/physiol Actions

β-Cyano-L-alanine (BCA) is used as a cystathione γ-lyase (CSE) inhibitor to study the physiological roles of hydrogen sulfide in processes such as angiogenesis and hypertension.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Studies on the reaction of D-amino acid oxidase with beta-cyano-D-alanine. Observation of an intermediary stable charge transfer complex.

R Miura et al.

Journal of biochemistry, 87(5), 1469-1481 (1980-05-01)

The reaction of D-amino acid oxidase [EC 1.4.3.3] (DAO) from porcine kidney with beta-cyano-D-alanine (D-BCNA) was studied. DAO was found to catalyze elimination of the cyano group as well as oxidation of D-BCNA. During the course of the reaction in

Role of hydrogen sulphide in haemorrhagic shock in the rat: protective effect of inhibitors of hydrogen sulphide biosynthesis.

Ying-Yuan Pamela Mok et al.

British journal of pharmacology, 143(7), 881-889 (2004-10-27)

Haemorrhagic shock (60 min) in the anaesthetized rat resulted in a prolonged fall in the mean arterial blood pressure (MAP) and heart rate (HR). Pre-treatment (30 min before shock) or post-treatment (60 min after shock) with inhibitors of cystathionine gamma

A conserved mechanism for nitrile metabolism in bacteria and plants.

Andrew J M Howden et al.

The Plant journal : for cell and molecular biology, 57(2), 243-253 (2008-09-13)

Pseudomonas fluorescens SBW25 is a plant growth-promoting bacterium that efficiently colonizes the leaf surfaces and rhizosphere of a range of plants. Previous studies have identified a putative plant-induced nitrilase gene (pinA) in P. fluorescens SBW25 that is expressed in the

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Global Trade Item Number

SKU	GTIN
C9650-250MG	04061832423043