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BXPC3 Cell Line human

NOTE: Both the cell line and DNA from the cell line may be available for this product. Please choose -1VL or VIAL for cells, or -DNA-5UG for DNA, 93120816, human pancreas, Epithelial

Synonym(s):

Biopsy Xenograft of Pancreatic Carcinoma Cell Line-3, BxPC-3 Cells

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About This Item

UNSPSC Code:
41106514
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biological source

human pancreas

description

Human primary pancreatic adenocarcinoma

packaging

tube of 5 μg 93120816-DNA-5UG
pkg of vial of cells 93120816-1VL

growth mode

Adherent

karyotype

2n = 59, near triploid

morphology

Epithelial

products

Mucin

receptors

Not specified

technique(s)

cell culture | mammalian: suitable

relevant disease(s)

cancer

shipped in

dry ice

storage temp.

−196°C

Application

BXPC3 cell line has been used to determine the biological and therapeutic importance of gastrin gene expression in pancreatic adenocarcinomas.
Tumourigenicity studies

Biochem/physiol Actions

Derived from a 61 year old female with a primary adenocarcinoma of the pancreas. BxPC-3 cells produce mucin and the tumour produced in a nude mouse is moderately well to poorly differentiated like the primary adenocarcinoma.
Human primary pancreatic adenocarcinoma
STR-PCR Data: Amelogenin: X
CSF1PO: 13
D13S317: 11
D16S539: 9,11
D5S818: 11
D7S820: 10,13
THO1: 9
TPOX: 8
vWA: 14,18

Preparation Note

RPMI 1640 + 2mM Glutamine + 10% Foetal Bovine Serum (FBS).
Split sub-confluent cultures (70-80%) 1:3 to 1:6 i.e. seeding at 2-4x10,000 cells/cm2 using 0.25% trypsin/EDTA; 5% CO2; 37°C.

Other Notes

Additional freight & handling charges may be applicable for Asia-Pacific shipments. Please check with your local Customer Service representative for more information.

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