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Merck
CN

C1

NOTE: Both the cell line and DNA from the cell line may be available for this product. Please choose -1VL or VIAL for cells, or -DNA-5UG for DNA.

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About This Item

UNSPSC Code:
41106514
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biological source

Mouse x Mouse Hybridoma

packaging

tube of 5 μg 99061825-DNA-5UG
pkg of vial of cells 99061825-1VL

ImmunoDon

(C57BL/6xBALB/c)F1

Myeloma

P3x63Ag8.653

Reactivity

Anti-HLA DQ2

technique(s)

cell culture | mammalian: suitable

isotype

IgM

shipped in

dry ice

storage temp.

−196°C

Immunogen

B cell line Co, HLA A1,B8 C7, DR3,DQ2

Application

Immunofluorescence, cytotoxicity

Biochem/physiol Actions

Mouse x Mouse hybridoma
The hybridoma C1 was produced from a (C57Bl/6xBALB/c)F1 mouse immunised with a single i.p. injection of the lymphoblastoid cell line Co and Bordetella pertussis organisms. The B cell line Co was expressing HLA A1, B8, C7, DR3 and DQ2. The mouse spleen was removed 3 days after immunisation and fused with the myeloma P3x63Ag8.653. C1 monoclonal antibodies were shown to react with cells expressing the class II antigen DQw2. The hybridoma is also known as COX IA2. C1 has been analysed in the International Histocompatibility Workshop 10 (IOW3105) and 12 (12W593).

Preparation Note

Maintain cultures between 3-9 x 100,000 cells/ml; 5% CO2; 37°C
RPMI 1640 + 2mM glutamine + 1mM NaP + 10% FBS

Other Notes

Additional freight & handling charges may be applicable for Asia-Pacific shipments. Please check with your local Customer Service representative for more information.

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