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About This Item
UNSPSC Code:
41122107
NACRES:
NB.13
Product Name
Corning® Costar® Transwell® cell culture inserts, TC treated, PET membrane, diam. 6.5 mm, pore size 8.0 μm, sterile
material
PET membrane
clear plate
flat bottom clear polystyrene wells
round wells
sterility
sterile
feature
lid
skirt
packaging
pack of 12 ea
case of 48 ea
manufacturer/tradename
Corning 3464
diam.
6.5 mm
membrane thickness × diam.
10 μm × 6.5 mm
size
24 wells
well working volume
0.6 mL
color
clear
pore size
8 μm
8.0 μm
binding type
Tissue Culture (TC)-treated surface
Related Categories
General description
The Transwell® cell culture inserts feature a distinctive self-centered and hanging design that effectively prevents the unwanted wicking of medium between the insert and outer well. This in turn ensures the uninterrupted and intact co-culturing of cells in the lower compartment, allowing for undisturbed cell growth and maintenance.
Application
The Corning® Costar® Transwell® cell culture inserts are well-suited for cell staining applications and various chemotaxis assays, including fibroblast migration studies, tumor invasion and metastasis, trans-migrational studies, and invasion inhibition research. The inserts have been used in:
- Transwell assay to study the role of TGF-β-MTA1-SMAD7-SMAD3-SOX4-EZH2 signaling axis in hepatocellular carcinoma cells
- MTT Assay to study GAS5-mediated signaling in osteosarcoma cells
- tri-cultured neuroinflammation model
Features and Benefits
- 10 μm thick transparent polyester membrane
- Treated for optimal cell attachment
- Sterilized by gamma radiation Lids included TC-treated surface 0.33 cm2 cell growth area
- Can be coated with a diverse range of extracellular matrices (ECM) and basement membrane extracts (BME)
- Optical clarity enables clear visualization of cell outlines when observed under phase contrast microscopy
- Offers compatibility with histochemical stains and fluorochromes for various cell staining applications
Legal Information
Corning is a registered trademark of Corning, Inc.
Costar is a registered trademark of Corning, Inc.
Transwell is a registered trademark of Corning, Inc.
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The CtBP1-HDAC1/2-IRF1 transcriptional complex represses the expression of the long noncoding RNA GAS5 in human osteosarcoma cells
Zhang X, et al.
International journal of biological and chemical sciences (2019)
Yan-Fang Zheng et al.
Journal of neurochemistry, 156(2), 249-261 (2020-09-06)
Neuroinflammation is believed to play a primary role in the pathogenesis of most neurodegenerative diseases including Alzheimer's disease, Parkinson's disease and schizophrenia. Currently, suitable in vitro neuroinflammation models for studying cellular interactions and inflammatory mechanisms at the neurovascular unit are
Aritro Nath et al.
Molecular cancer research : MCR, 19(2), 240-248 (2020-10-28)
Elevated uptake of saturated fatty acid palmitate is associated with metastatic progression of cancer cells; however, the precise signaling mechanism behind the phenomenon is unclear. The loss of cell adhesion proteins, such as desmoplakin (DSP), is a key driving event
Rodrigo Berzaghi et al.
Cancers, 11(5) (2019-05-22)
The abilities of cancer-associated fibroblasts (CAFs) to regulate immune responses in the context of radiotherapy remain largely unknown. This study was undertaken to determine whether ionizing radiation alters the CAF-mediated immunoregulatory effects on macrophages. CAFs were isolated from freshly-resected non-small
Kangjun Zhang et al.
Cancer management and research, 13, 7087-7099 (2021-09-18)
Enhancer of zeste homolog 2 (EZH2) is implicated in hepatocellular carcinoma (HCC), but whether transforming growth factor-β (TGF-β)-metastasis associated 1 (MTA1)-SMAD7-SMAD3-SRY-Box Transcription Factor 4 (SOX4)-EZH2 signaling axis, in which EZH2 participates, is also involved in HCC remained unknown. Data on
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