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Merck
CN

D0400

9,11-Dideoxy-9α,11α-epoxymethanoprostaglandin F

Synonym(s):

U44069

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About This Item

Empirical Formula (Hill Notation):
C21H34O4
CAS Number:
Molecular Weight:
350.49
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352211
MDL number:
Form:
liquid
Quality level:
Technical Service
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description

solution in methyl acetate

Quality Level

form

liquid

shipped in

dry ice

storage temp.

−20°C

SMILES string

CCCCC[C@H](O)\C=C\[C@H]1[C@@H]2CO[C@@H](C2)[C@@H]1C\C=C/CCCC(O)=O

InChI

1S/C21H34O4/c1-2-3-6-9-17(22)12-13-18-16-14-20(25-15-16)19(18)10-7-4-5-8-11-21(23)24/h4,7,12-13,16-20,22H,2-3,5-6,8-11,14-15H2,1H3,(H,23,24)/b7-4-,13-12+/t16-,17-,18-,19+,20-/m0/s1

InChI key

DJKDIKIDYDXHDD-IGUVKOCZSA-N

Biochem/physiol Actions

Prostaglandin F analogue; thromboxane A2/prostaglandin H2 mimetic.

Disclaimer

Supply conditions do not apply to the regions and states of Brazil: North, Northeast, Mato Grosso do Sul, Mato Grosso, and Rio Grande do Sul.


pictograms

FlameExclamation mark

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

target_organs

Central nervous system

supp_hazards

Storage Class

3 - Flammable liquids

wgk

WGK 2

flash_point_f

8.6 °F

flash_point_c

-13 °C

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

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Articles

Discover Bioactive Small Molecules for Lipid Signaling Research


I Mark Bowen et al.
The Journal of heart valve disease, 13(4), 593-599 (2004-08-18)
The equine aortic valve is subject to non-inflammatory degenerative changes, associated with aortic valvular regurgitation (AR). This disease shares pathological and epidemiological features with AR in humans, and may serve as a useful model to study in-vitro functional responses associated
J A Scott et al.
American journal of respiratory and critical care medicine, 154(3 Pt 1), 629-632 (1996-09-01)
Nonadrenergic noncholinergic (NANC) vasodilator mechanisms may contribute to the maintenance of low vascular resistance characteristic of the pulmonary circulation. Previous studies have demonstrated that nitric oxide (NO) is the principal NANC neurotransmitter in guinea pig pulmonary arteries. We examined whether
Pei-Yung Hsu et al.
Archives of biochemistry and biophysics, 416(1), 38-46 (2003-07-16)
Thromboxane A2 synthase (TXAS) binds to the endoplasmic reticulum membrane and catalyzes both an isomerization of prostaglandin H2 (PGH2) to form thromboxane A2 (TXA2) and a fragmentation of PGH2 to form 12-hydroxy-5,8,10-heptadecatrienoic acid (HHT) and malondialdehyde (MDA). TXAS is a



Global Trade Item Number

SKUGTIN
D0400-10MG04061832785288
D0400-5MG04061833557655
D0400-1MG04061826674376