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Merck
CN

D0929

3,3′-Diheptyloxacarbocyanine iodide

Synonym(s):

DiOC7(3)

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About This Item

Empirical Formula (Hill Notation):
C31H41IN2O2
CAS Number:
Molecular Weight:
600.57
UNSPSC Code:
12171500
PubChem Substance ID:
MDL number:
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fluorescence

λex 484 nm; λem 504 nm in methanol

SMILES string

[I-].CCCCCCCN1C(\Oc2ccccc12)=C\C=C\c3oc4ccccc4[n+]3CCCCCCC

InChI

1S/C31H41N2O2.HI/c1-3-5-7-9-15-24-32-26-18-11-13-20-28(26)34-30(32)22-17-23-31-33(25-16-10-8-6-4-2)27-19-12-14-21-29(27)35-31;/h11-14,17-23H,3-10,15-16,24-25H2,1-2H3;1H/q+1;/p-1

InChI key

ANJZLSIIEGUCQL-UHFFFAOYSA-M

pictograms

Health hazardExclamation mark

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type P2 (EN 143) respirator cartridges

Regulatory Information

新产品

This item has


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Z Liu et al.
Plant physiology, 84(4), 1385-1390 (1987-08-01)
Selected fluorescent dyes were tested for uptake by mitochrondria in intact cells of barley, maize, and onion. The cationic cyanine dye 3,3'-diheptyloxacarbocyanine iodide [DiOC(7)(3)] accumulated in mitochondria within 15 to 30 minutes without appreciable staining of other protoplasmic constituents. The
Jennifer H E Baker et al.
PloS one, 8(10), e76832-e76832 (2013-11-10)
Many cancer research efforts focus on exploiting genetic-level features that may be targeted for therapy. Tissue-level features of the tumour microenvironment also represent useful therapeutic targets. Here we investigate the presence of low oxygen tension and sensitivity to NOS inhibition
Alastair H Kyle et al.
Molecular cancer therapeutics, 13(11), 2727-2737 (2014-08-22)
The ability of a panel of camptothecin derivatives to access the tumor compartment was evaluated to determine the mechanisms by which the architecture of solid tumors may act to limit their activity. Microregional localization and activity of members of the
M J Trotter et al.
British journal of cancer, 59(5), 706-709 (1989-05-01)
An intravenously administered fluorescent carbocyanine dye, DiOC7(3), has been evaluated for use in conjunction with Hoechst 33342 as a marker of murine tumour vasculature. DiOC7(3) stains cells immediately adjacent to blood vessels and thus, like Hoechst 33342, outlines perfused tumour

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