D0929
3,3′-Diheptyloxacarbocyanine iodide
别名:
DiOC7(3)
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关于此项目
经验公式（希尔记法）:
C31H41IN2O2
化学文摘社编号:
分子量:
600.57
UNSPSC Code:
12171500
PubChem Substance ID:
MDL number:
fluorescence
λex 484 nm; λem 504 nm in methanol
SMILES string
[I-].CCCCCCCN1C(\Oc2ccccc12)=C\C=C\c3oc4ccccc4[n+]3CCCCCCC
InChI
1S/C31H41N2O2.HI/c1-3-5-7-9-15-24-32-26-18-11-13-20-28(26)34-30(32)22-17-23-31-33(25-16-10-8-6-4-2)27-19-12-14-21-29(27)35-31;/h11-14,17-23H,3-10,15-16,24-25H2,1-2H3;1H/q+1;/p-1
InChI key
ANJZLSIIEGUCQL-UHFFFAOYSA-M
signalword
Danger
hcodes
Hazard Classifications
Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type P2 (EN 143) respirator cartridges
法规信息
新产品
此项目有
Z Liu et al.
Plant physiology, 84(4), 1385-1390 (1987-08-01)
Selected fluorescent dyes were tested for uptake by mitochrondria in intact cells of barley, maize, and onion. The cationic cyanine dye 3,3'-diheptyloxacarbocyanine iodide [DiOC(7)(3)] accumulated in mitochondria within 15 to 30 minutes without appreciable staining of other protoplasmic constituents. The
Jennifer H E Baker et al.
PloS one, 8(10), e76832-e76832 (2013-11-10)
Many cancer research efforts focus on exploiting genetic-level features that may be targeted for therapy. Tissue-level features of the tumour microenvironment also represent useful therapeutic targets. Here we investigate the presence of low oxygen tension and sensitivity to NOS inhibition
Alastair H Kyle et al.
Molecular cancer therapeutics, 13(11), 2727-2737 (2014-08-22)
The ability of a panel of camptothecin derivatives to access the tumor compartment was evaluated to determine the mechanisms by which the architecture of solid tumors may act to limit their activity. Microregional localization and activity of members of the
M J Trotter et al.
British journal of cancer, 59(5), 706-709 (1989-05-01)
An intravenously administered fluorescent carbocyanine dye, DiOC7(3), has been evaluated for use in conjunction with Hoechst 33342 as a marker of murine tumour vasculature. DiOC7(3) stains cells immediately adjacent to blood vessels and thus, like Hoechst 33342, outlines perfused tumour
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