D1411
d-Desthiobiotin
≥98% (TLC)
Synonym(s):
5-Methyl-2-oxo-4-imidazolidinehexanoic acid
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About This Item
Empirical Formula (Hill Notation):
C10H18N2O3
CAS Number:
Molecular Weight:
214.26
EC Number:
MDL number:
UNSPSC Code:
12352200
eCl@ss:
34058011
PubChem Substance ID:
NACRES:
NA.25
Quality Level
Assay
≥98% (TLC)
form
powder
storage temp.
2-8°C
SMILES string
C[C@@H]1NC(=O)N[C@@H]1CCCCCC(O)=O
InChI
1S/C10H18N2O3/c1-7-8(12-10(15)11-7)5-3-2-4-6-9(13)14/h7-8H,2-6H2,1H3,(H,13,14)(H2,11,12,15)/t7-,8+/m0/s1
InChI key
AUTOLBMXDDTRRT-JGVFFNPUSA-N
Application
d-Desthiobiotin has been used as a component of elution buffers:
- to elute the precipitated proteins from the resin during coimmunoprecipitation
- to elute human Cdc45–MCM–GINS (CMG) helicase during chromatographic protein purification
- to elute the heterodimeric kinesin family member 3A/B (KIF3A/B) and kinesin associated protein 3 (KAP3)-binding APC armadillo (APCARM) domain during chromatographic purification
d-Desthiobiotin is used in affinity chromatography and protein chromatography. d-Desthiobiotin can be used for protein labeling, detection and isolation.
Biochem/physiol Actions
Desthiobiotin is a non-sulfur containing biotin derivative that binds less strongly to biotin-binding proteins and is easily dislocated by biotin.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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