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Merck
CN

D1444

6,2′-Dihydroxyflavone

≥98% (HPLC), powder

Synonym(s):

6-hydroxy-2-(2-hydroxyphenyl)-4H-1-benzopyran-4-one, DHF

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About This Item

Empirical Formula (Hill Notation):
C15H10O4
Molecular Weight:
254.24
NACRES:
NA.77
UNSPSC Code:
12352200

Key Documents

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Product Name

6,2′-Dihydroxyflavone, ≥98% (HPLC), powder

assay

≥98% (HPLC)

form

powder

color

white

solubility

DMSO: >10 mg/mL

storage temp.

room temp

Biochem/physiol Actions

6,2′-Dihydroxyflavone is a partial inverse agonist at GABAA receptors with α-subunit selectivity.

Features and Benefits

This compound is featured on the GABAA Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

pictograms

Skull and crossbonesCorrosion
GHS06,GHS05

signalword

Danger

hcodes

H301,H318

Hazard Classifications

Acute Tox. 3 Oral - Eye Dam. 1

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
117K4714

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Feng Wang et al.
Neuropharmacology, 53(4), 574-582 (2007-08-08)
Neuroactivity of a number of flavonoids is mediated by modulation of type A gamma-aminobutyric acid (GABA(A)) receptor function via benzodiazepine sites, mostly as partial agonists. In the present study, 6,2'-dihydroxyflavone (DHF) was characterized for potential inverse agonistic activity, and its

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