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Merck
CN

D3132

Silver diethyldithiocarbamate

Synonym(s):

DETC, Diethyldithiocarbamic acid silver salt

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About This Item

Linear Formula:
(C2H5)2NCSSAg
CAS Number:
Molecular Weight:
256.14
UNSPSC Code:
12171500
NACRES:
NA.47
PubChem Substance ID:
EC Number:
216-003-7
Beilstein/REAXYS Number:
3718150
MDL number:
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form

powder

Quality Segment

mp

172-175 °C (lit.)

solubility

pyridine: 25 mg/mL, clear, yellow

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

2-8°C

SMILES string

CCN(CC)C(=S)S[Ag]

InChI

1S/C5H11NS2.Ag/c1-3-6(4-2)5(7)8;/h3-4H2,1-2H3,(H,7,8);/q;+1/p-1

InChI key

NSVHDIYWJVLAGH-UHFFFAOYSA-M

Application

Spin trap used in conjunction with Fe2+ to detect NO in brain, kidney, liver, and other tissues. Simultaneous direct measurement of NO* and pO2 has been reported. A copper chelator, it has been used to quantitate copper in biological materials by ESR and is an inhibitor of superoxide dismutase, ascorbate oxidase, and other enzymes.
Also used for colorimetric determination of small quantities of arsenic.
Silver diethyldithiocarbamate has been used in cell culture.
Also used for colorimetric determination of small quantities of arsenic
Spin trap used in conjunction with Fe2+ to detect NO in brain, kidney, liver, and other tissues. Simultaneous direct measurement of NO* and pO2 has been reported. A copper chelator, it has been used to quantitate copper in biological materials by ESR and is an inhibitor of superoxide dismutase, ascorbate oxidase, and other enzymes.

Biochem/physiol Actions

Inhibits induction of macrophage nitric oxide synthase.
Silver diethyldithiocarbamate (AgDDC) is used to estimate the level of arsenic in human.
Inhibits induction of macrophage nitric oxide synthase.


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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