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Merck
CN

D3132

Silver diethyldithiocarbamate

Synonym(s):

DETC, Diethyldithiocarbamic acid silver salt

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About This Item

Linear Formula:
(C2H5)2NCSSAg
CAS Number:
Molecular Weight:
256.14
UNSPSC Code:
12171500
NACRES:
NA.47
PubChem Substance ID:
EC Number:
216-003-7
Beilstein/REAXYS Number:
3718150
MDL number:
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form

powder

Quality Level

mp

172-175 °C (lit.)

solubility

pyridine: 25 mg/mL, clear, yellow

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

2-8°C

SMILES string

CCN(CC)C(=S)S[Ag]

InChI

1S/C5H11NS2.Ag/c1-3-6(4-2)5(7)8;/h3-4H2,1-2H3,(H,7,8);/q;+1/p-1

InChI key

NSVHDIYWJVLAGH-UHFFFAOYSA-M

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Application

Spin trap used in conjunction with Fe2+ to detect NO in brain, kidney, liver, and other tissues. Simultaneous direct measurement of NO* and pO2 has been reported. A copper chelator, it has been used to quantitate copper in biological materials by ESR and is an inhibitor of superoxide dismutase, ascorbate oxidase, and other enzymes.
Also used for colorimetric determination of small quantities of arsenic.
Silver diethyldithiocarbamate has been used in cell culture.
Also used for colorimetric determination of small quantities of arsenic
Spin trap used in conjunction with Fe2+ to detect NO in brain, kidney, liver, and other tissues. Simultaneous direct measurement of NO* and pO2 has been reported. A copper chelator, it has been used to quantitate copper in biological materials by ESR and is an inhibitor of superoxide dismutase, ascorbate oxidase, and other enzymes.

Biochem/physiol Actions

Inhibits induction of macrophage nitric oxide synthase.
Silver diethyldithiocarbamate (AgDDC) is used to estimate the level of arsenic in human.
Inhibits induction of macrophage nitric oxide synthase.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Determination of the level of arsenic in human bodies (population of Basle).
Baumler J, et al.
International Journal of Legal Medicine, 64(2), 56-61 (1968)
Induction of the Expressions of Antioxidant Enzymes by Luteinizing Hormone in the Bovine Corpus Luteum.
Kawaguchi S, et al.
Journal of Reproduction and Development, 59(3), 219-224 (2013)
Seth H Frisbie et al.
Environmental health perspectives, 113(9), 1196-1204 (2005-09-06)
All of Bangladesh's approximately 10 million drinking-water tube wells must be periodically tested for arsenic. The magnitude of this task and the limited resources of Bangladesh have led to the use of low-cost, semiquantitative field kits that measure As to
Sanjoy K Maji et al.
Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering, 42(7), 989-996 (2007-06-15)
The efficiency of a locally available laterite soil in removing both arsenite and arsenate from aqueous medium by adsorption was evaluated. It was observed that in batch experiment conducted at 0.5 mg/L initial concentration of arsenic, laterite soil could remove
D Brune et al.
Swedish dental journal, 4(3), 125-128 (1980-01-01)
The reliability of the method for analysis for arsenic in dental cements according to the international standard ISO 2590 has been reinvestigated using nuclear tracer techniques and intercomparison of results obtained for the arsenic content of various cements by means

Global Trade Item Number

SKUGTIN
D3132-5G04061833562963
D3132-25G04061833562956

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