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Merck
CN

D4266

3-(Decyldimethylammonio)­propane­sulfonate inner salt

zwitterionic detergent

Synonym(s):

Caprylyl sulfobetaine, SB3-10

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About This Item

Linear Formula:
CH3(CH2)9N+(CH3)2CH2CH2CH2SO3-
CAS Number:
15163-36-7
Molecular Weight:
307.49
UNSPSC Code:
12161900
NACRES:
NA.25
PubChem Substance ID:
24893849
MDL number:
MFCD00036908
Beilstein/REAXYS Number:
3967284

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InChI

1S/C15H33NO3S/c1-4-5-6-7-8-9-10-11-13-16(2,3)14-12-15-20(17,18)19/h4-15H2,1-3H3

SMILES string

CCCCCCCCCC[N+](C)(C)CCCS([O-])(=O)=O

InChI key

WKALLSVICJPZTM-UHFFFAOYSA-N

assay

≥98.0% (TLC)

form

powder

mol wt

micellar avg mol wt 12,600

aggregation number

41

technique(s)

enzyme immunoassay: suitable, protein purification: suitable, protein quantification: suitable

conductivity

<20 μmho per cm at 24 °C (0.1 M aqueous solution)

CMC

25-40 mM (20-25°C)

Quality Level

200

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General description

3-(Decyldimethylammonio)­propane­sulfonate inner salt, a zwitterionic surfactant, is a sulfobetaine. Sulfobetaines contain a positively charged quaternary ammonium group and a negatively charged sulfonic group.

Application

3-(Decyldimethylammonio)­propane­sulfonate inner salt was used:
  • In a study to demonstrate a polyurethane chip that electrostatically binds to immunoglobulin G (IgG).
  • In a study to describe a method for isolating a high yield of Arabidopsis chloroplasts.
  • Solubilization of oleosins.
Zwitterionic detergent used for protein solubilization.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000535300
0000535300
0000523421
0000523421
0000509937

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Effects of long-chains of zwitterionic micelles on binding constants of triflusal and acetylsalicylic acid.
Ferrit M, et al.
Colloids and Surfaces. A, Physicochemical and Engineering Aspects, 345(1), 26-30 (2009)
Solubilization conditions for hydrophobic membrane protein, oleosin, in soybeans
Kim, H., et al.
Biotechnology and Bioprocess Engineering: BBE, 12, 542-542 (2007)
Synthesis and surface-active properties of sulfobetaine-type zwitterionic gemini surfactants.
Yoshimura T, et al.
Colloids and Surfaces. A, Physicochemical and Engineering Aspects, 273(1), 208-212 (2006)
L I Hochstein et al.
Biochemical and biophysical research communications, 147(1), 295-300 (1987-08-31)
A membrane-bound ATPase from Halobacterium saccharovorum was solubilized using sodium deoxycholate and Zwittergent 3-10 and purified by hydrophobic and ammonium sulfate-mediated chromatography. The enzyme, which had a molecular mass of 350 kDa, was composed of two major (87 and 60
Sybille E Kubis et al.
Methods in molecular biology (Clifton, N.J.), 425, 171-186 (2008-03-29)
A major area of research in the postgenomic era has been the proteomic analysis of various subcellular and suborganellar compartments. The success of these studies is to a large extent dependent upon efficient protocols for the preparation of highly pure
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