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D4902

Sigma-Aldrich

Dexamethasone

powder, BioReagent, suitable for cell culture, ≥97%

Synonym(s):

(11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione, 9α-Fluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione, 9α-Fluoro-16α-methylprednisolone, Prednisolone F

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5 EA
¥871.93

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5 EA
¥871.93

About This Item

Empirical Formula (Hill Notation):
C22H29FO5
CAS Number:
Molecular Weight:
392.46
Beilstein:
2066651
EC Number:
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.75
Biological source:
synthetic
Form:
powder

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biological source

synthetic

Quality Level

product line

BioReagent

Assay

≥97%

form

powder

potency

4-500 ng/mL

technique(s)

cell culture | mammalian: suitable
single cell analysis: suitable

mp

262-264 °C (lit.)

solubility

methanol: 25 mg/mL

shipped in

ambient

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This Item
NORS205001NORS4255001NORS505001
manufacturer/tradename

Norell S-2.5-500-1

manufacturer/tradename

Norell S-2.0-500-1

manufacturer/tradename

Norell S-4.25-500-1

manufacturer/tradename

Norell S-5.0-500-1

material

colorless tube

material

colorless tube

material

colorless tube

material

colorless tube

packaging

pack of 5 ea

packaging

pack of 5 ea

packaging

pack of 5 ea

packaging

pack of 5 ea

feature

neck thread push fit

feature

neck thread push fit

feature

neck thread push fit

feature

neck thread push fit

capacity

120 μL

capacity

-

capacity

-

capacity

-

wall thickness

0.4 mm

wall thickness

0.4 mm

wall thickness

0.82 mm

wall thickness

0.77 mm

Application

Dexamethasone is used to study apoptosis, cell signaling pathways, cell differentiation[1][2] and gene expression.[3][4][5]

Biochem/physiol Actions

Glucocorticoid anti-inflammatory agent
Glucocorticoid anti-inflammatory agent. Regulates T cell survival, growth, and differentiation. Inhibits the induction of nitric oxide synthase.
It is poorly metabolized in the body and has great affinity and bioavailability.[6]

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Physical form

powder 2-8 °C; stock-frozen in working aliquots, avoid repeated freeze/thaw

Preparation Note

To prepare 20 μg/ml stock solution, add 1ml absolute ethanol per mg product; gently swirl to dissolve. Add 49 ml sterile medium per ml of ethanol added, while mixing, to acheive final concentration of 20 μg/ml.

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Description
Pricing

Pictograms

Health hazard

Signal Word

Danger

Hazard Statements

Hazard Classifications

Repr. 1B

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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