biological source
synthetic (microbial fermentation/ cell culture)
Quality Level
Assay
96% (NT)
form
liquid
refractive index
n20/D 1.398 (lit.)
bp
93-94 °C/18 mmHg (lit.)
density
1.101 g/mL at 25 °C (lit.)
shipped in
wet ice
storage temp.
2-8°C
SMILES string
CCOC(=O)OC(=O)OCC
InChI
1S/C6H10O5/c1-3-9-5(7)11-6(8)10-4-2/h3-4H2,1-2H3
InChI key
FFYPMLJYZAEMQB-UHFFFAOYSA-N
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General description
Application
Biochem/physiol Actions
It inhibits the ryanodine binding to ryanodine/Ca2+ receptor channels in skeletal muscle in a dose and time dependent manner and increases the Ca2+ permeability of SR vesicles.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point(F)
156.2 °F - closed cup
Flash Point(C)
69 °C - closed cup
Personal Protective Equipment
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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705578-5MG-PW
PL860-CGA/SHF-1EA
MMYOMAG-74K-13
1000309185
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How to Find a Lot/Batch Number for COA
Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.
Aldrich Products
For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').
For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').
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In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.
What is the stability of Product D5758, Diethyl pyrocarbonate, at room temperature?
The material is stable at room temperature as long as it is protected from moisture. We do recommend 2-8 °C for its storage.
How can I tell if Product D5758, Diethyl pyrocarbonate, has degraded?
DEPC breaks down to ethanol and carbon dioxide. The carbon dioxide builds up pressure inside the bottle; when opened, it will degas and/or bubble out of the bottle.
What buffers can I use with Product D5758, Diethyl pyrocarbonate (DEPC)?
DEPC reacts with amines, thiols, and alcohols. Any buffer that contains an amine, e.g.., Trizma, should not be used. View this information on the product information sheet (under Documents, above.
What type of container should I use to handle Product D5758, Diethyl pyrocarbonate (DEPC)?
Glassware is preferable since some plastics, e.g.., polycarbonate, are known to react with DEPC.
Why is stirring or shaking necessary when making RNAse-free water for use with Product D5758, Diethyl pyrocarbonate?
DEPC is not very soluble in water. Stirring and/or shaking is necessary to suspend DEPC in water.
What is the best way to use Product D5758, Diethyl pyrocarbonate, to inactivate RNAse?
Add DEPC directly to the water to yield a 0.1 % solution. Shake vigorously and allow to set overnight at room temperature with the lid loose or incubated for 2 hours at 37 °C. The solution is then autoclaved 15 minutes for each liter.
Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
How do I get lot-specific information or a Certificate of Analysis?
The lot specific COA document can be found by entering the lot number above under the "Documents" section.
How do I find price and availability?
There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote. USA customers: 1-800-325-3010 or view local office numbers.
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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Articles
Nuclease-free water (or PCR water) is needed in molecular biology to avoid sample degradation during PCR, sequencing, etc. Ultrafiltration provides a quicker, safer, and more sustainable alternative to DEPC treatment when preparing RNase-free and DNase-free water.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
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