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Merck
CN

D5766

5,5-Dimethyl-1-pyrroline N-oxide

≥97%

Synonym(s):

DMPO

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About This Item

Empirical Formula (Hill Notation):
C6H11NO
CAS Number:
Molecular Weight:
113.16
UNSPSC Code:
12352200
NACRES:
NA.77
PubChem Substance ID:
EC Number:
222-011-1
Beilstein/REAXYS Number:
107603
MDL number:
Assay:
≥97% (GC), ≥97%
Form:
solid
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assay

≥97% (GC), ≥97%

form

solid

refractive index

n20/D 1.496 (lit.)

bp

75 °C/0.4 mmHg (lit.)

mp

25-29 °C (lit.)

density

1.015 g/mL at 25 °C (lit.)

shipped in

wet ice

storage temp.

−20°C

SMILES string

CC1(C)CCC=[N+]1[O-]

InChI

1S/C6H11NO/c1-6(2)4-3-5-7(6)8/h5H,3-4H2,1-2H3

InChI key

VCUVETGKTILCLC-UHFFFAOYSA-N

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Application

5,5-Dimethyl-1-pyrroline N-oxide has been used as a spin trapping reagent to detect free radicals in electron paramagnetic resonance (EPR) based reactions.
Neuroprotective agent; nitric oxide spin trap. Used to study radicals formed by enzymatic acetaldehyde oxidation.
Neuroprotective agent; nitric oxide spin trap. Used to study radicals formed by enzymatic acetaldehyde oxidation. Incubation of lymphocytes with DMPO decreased DNA damage by NiCl2.

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

203.0 °F - closed cup

flash_point_c

95 °C - closed cup

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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Wan-Ook Ji et al.
Scientific reports, 9(1), 19837-19837 (2019-12-29)
Medical treatment utilizing non-thermal plasma is based on the production of reactive oxygen species (ROS) and their interactions with biomatters. On the basis of empirical data from practices, plasma treatment has been planned with regard to the setup of a
Xiaoguang Duan et al.
Small (Weinheim an der Bergstrasse, Germany), 11(25), 3036-3044 (2015-03-20)
Sulfur and nitrogen co-doped reduced graphene oxide (rGO) is synthesized by a facile method and demonstrated remarkably enhanced activities in metal-free activation of peroxymonosulfate (PMS) for catalytic oxidation of phenol. Based on first-order kinetic model, S-N co-doped rGO (SNG) presents
Mitochondrial O 2 and H 2O 2 mediate glucose deprivation-induced cytotoxicity and oxidative stress in human cancer cells
Ahmad IM, et al.
The Journal of biological chemistry (2004)
Nanoparticle-induced oxidation of corona proteins initiates an oxidative stress response in cells
Jayaram DT, et al.
Nanoscale, 9(22), 7595-7601 (2017)
Sambuddha Banerjee et al.
Free radical biology & medicine, 53(6), 1317-1326 (2012-07-31)
We compared oxygenation and anaerobic oxidation reactions of a purified complex of human hemoglobin (Hb) and haptoglobin (Hb-Hp) to those of uncomplexed Hb. Under equilibrium conditions, Hb-Hp exhibited active-site heterogeneity and noncooperative, high-affinity O(2) binding (n(1/2)=0.88, P(1/2)=0.33 mm Hg in

Global Trade Item Number

SKUGTIN
D5766-1G04061833586778
D5766-250MG04061833586785

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