D6140
Demeclocycline hydrochloride
powder or crystals, suitable for cell culture
Synonym(s):
7-Chloro-6-demethyltetracycline hydrochloride, Demethylchlorotetracycline hydrochloride
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About This Item
Product Name
Demeclocycline hydrochloride, powder or crystals
InChI key
GVSJQNRGSCOSNJ-KBHRXELFSA-N
InChI
1S/C21H21ClN2O8.ClH/c1-24(2)14-7-5-6-10(16(27)12-9(25)4-3-8(22)11(12)15(6)26)18(29)21(7,32)19(30)13(17(14)28)20(23)31;/h3-4,6-7,14-15,25-26,28-29,32H,5H2,1-2H3,(H2,23,31);1H/t6-,7-,14-,15-,21-;/m0./s1
SMILES string
Cl[H].[H][C@]12C[C@@]3([H])[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]3(O)C(O)=C1C(=O)c4c(O)ccc(Cl)c4[C@H]2O
assay
89.5-102.0% anhydrous basis
form
powder or crystals
technique(s)
cell culture | mammalian: suitable
solubility
soluble (1 mg/mL of Demeclocycline Hydrochloride in 0.01 N hydrochloric acid)
antibiotic activity spectrum
Gram-negative bacteria
Gram-positive bacteria
mode of action
protein synthesis | interferes
storage temp.
−20°C
Quality Level
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General description
Biochem/physiol Actions
signalword
Warning
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Muta. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Regulatory Information
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How does the storage temperature relate to shipping conditions?
The storage conditions that a Sigma-Aldrich catalog and label recommend for products are deliberately conservative. For many products, long-term storage at low temperatures will increase the time during which they are expected to remain in specification and therefore are labeled accordingly. Where short-term storage, shipping time frame, or exposure to conditions other than those recommended for long-term storage will not affect product quality, Sigma-Aldrich will ship at ambient temperature. The products sensitive to short-term exposure to conditions other than their recommended long-term storage are shipped on wet or dry ice. Ambient temperature shipping helps to control shipping costs for our customers. At any time, our customers can request wet- or dry-ice shipment, but the special handling is at customer expense if our product history indicates that the product is stable for regular shipment. See Shipping and Storage for more information.
Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
How do I get lot-specific information or a Certificate of Analysis?
The lot specific COA document can be found by entering the lot number above under the "Documents" section.
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What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
What is the solubility of Product D6140, Demeclocycline hydrochloride?
Product D6140, Demeclocycline hydrochloride, has been found to be soluble in water at 20mg/ml, with heat as needed. This will yield a clear yellow to very dark green-yellow solution.
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