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Merck
CN

D6149

1-Deoxy-1-morpholino-D-fructose

≥98% (TLC)

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About This Item

Empirical Formula (Hill Notation):
C10H19NO6
CAS Number:
6291-16-3
Molecular Weight:
249.26
UNSPSC Code:
12352201
NACRES:
NA.25
PubChem Substance ID:
24894004
MDL number:
MFCD00166980
Beilstein/REAXYS Number:
19582

Key Documents

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Product Name

1-Deoxy-1-morpholino-D-fructose, ≥98% (TLC)

InChI

1S/C10H19NO6/c12-6-8(14)10(16)9(15)7(13)5-11-1-3-17-4-2-11/h8-10,12,14-16H,1-6H2/t8-,9-,10-/m1/s1

SMILES string

OC[C@@H](O)[C@@H](O)[C@H](O)C(=O)CN1CCOCC1

InChI key

JPANQHVKLYKLEB-OPRDCNLKSA-N

assay

≥98% (TLC)

form

powder

technique(s)

thin layer chromatography (TLC): suitable

color

white to off-white

mp

147 °C

solubility

methanol: 19.60-20.40 mg/mL, clear, colorless to faintly yellow

storage temp.

−20°C

Quality Level

200

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Related Categories

Application

DMF (1-Deoxy-1-morpholino-D-fructose), an analog of the 1-desoxy-1-amino-fructose radical found in glycated proteins, has been used in the development of glycation assays.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000483762
0000483762
0000458212
0000436120
0000436120

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J E Howey et al.
Clinical chemistry, 33(2 Pt 1), 269-272 (1987-02-01)
Methodological problems with the assay of fructosamine in serum--standardization, matrix effects, and dependence on buffer pH--have been minimized with a method involving colorimetric assay of each specimen and subsequent re-assay after standard addition of 1-deoxy-1-morpholinofructose. Absorbance at optimum wavelength of
R N Johnson et al.
Clinical chemistry, 32(2), 368-370 (1986-02-01)
We investigated the ability of the fructosamine assay to detect glycation of serum proteins. We incubated both whole human serum and serum protein fractions in vitro with [14C]glucose, and analyzed for reducing activity and for uptake of 14C by protein.
G Delpierre et al.
The Biochemical journal, 352 Pt 3, 835-839 (2000-12-06)
Intact human erythrocytes catalyse the conversion of fructose into fructose 3-phosphate with an apparent K(m) of 30 mM [Petersen, Kappler, Szwergold and Brown (1992) Biochem. J. 284, 363-366]. The physiological significance of this process is still unknown. In the present
Permal Deo et al.
International journal of food sciences and nutrition, 71(6), 706-714 (2020-01-11)
This study investigated the role of non-nutritive sweeteners in the formation of advanced glycation end-products (AGEs) and their reactive intermediates using endogenous and exogenous models. In the endogenous model, xylitol and sorbitol formed similar levels of reactive intermediates compared to
Matthew W McDonald et al.
Journal of diabetes research, 2018, 8485624-8485624 (2018-08-18)
Intensive insulin therapy (IIT; 4-7 mmol/L) is the preferred treatment for type 1 diabetes mellitus (T1DM) patients to reduce the risk of cardiovascular disease (CVD). However, this treatment strategy has been questioned as it is accompanied with a sedentary lifestyle leading
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