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Merck
CN

D6149

1-Deoxy-1-morpholino-D-fructose

≥98% (TLC)

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About This Item

Empirical Formula (Hill Notation):
C10H19NO6
CAS Number:
6291-16-3
Molecular Weight:
249.26
UNSPSC Code:
12352201
NACRES:
NA.25
PubChem Substance ID:
24894004
MDL number:
MFCD00166980
Beilstein/REAXYS Number:
19582

Key Documents

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InChI

1S/C10H19NO6/c12-6-8(14)10(16)9(15)7(13)5-11-1-3-17-4-2-11/h8-10,12,14-16H,1-6H2/t8-,9-,10-/m1/s1

SMILES string

OC[C@@H](O)[C@@H](O)[C@H](O)C(=O)CN1CCOCC1

InChI key

JPANQHVKLYKLEB-OPRDCNLKSA-N

assay

≥98% (TLC)

form

powder

technique(s)

thin layer chromatography (TLC): suitable

color

white to off-white

mp

147 °C

solubility

methanol: 19.60-20.40 mg/mL, clear, colorless to faintly yellow

storage temp.

−20°C

Quality Level

200

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Related Categories

Application

DMF (1-Deoxy-1-morpholino-D-fructose), an analog of the 1-desoxy-1-amino-fructose radical found in glycated proteins, has been used in the development of glycation assays.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000483762
0000483762
0000458212
0000436120
0000436120

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Kenia Vázquez-Sánchez et al.
Food chemistry, 261, 253-259 (2018-05-10)
Antioxidant dietary fiber extracted from spent coffee grounds (FSCG) was evaluated as a potential functional food ingredient when incorporated in a food model (biscuits), and digested in vitro under simulated human gastrointestinal conditions. FSCG added to biscuits increased its total
Yan Wei et al.
BMC cell biology, 10, 10-10 (2009-02-17)
D-ribose in cells and human serum participates in glycation of proteins resulting in advanced glycation end products (AGEs) that affect cell metabolism and induce cell death. However, the mechanism by which D-ribose-glycated proteins induce cell death is still unclear. Here
J E Howey et al.
Clinical chemistry, 33(2 Pt 1), 269-272 (1987-02-01)
Methodological problems with the assay of fructosamine in serum--standardization, matrix effects, and dependence on buffer pH--have been minimized with a method involving colorimetric assay of each specimen and subsequent re-assay after standard addition of 1-deoxy-1-morpholinofructose. Absorbance at optimum wavelength of
R N Johnson et al.
Clinical chemistry, 32(2), 368-370 (1986-02-01)
We investigated the ability of the fructosamine assay to detect glycation of serum proteins. We incubated both whole human serum and serum protein fractions in vitro with [14C]glucose, and analyzed for reducing activity and for uptake of 14C by protein.
Ya-Jie Xu et al.
Clinica chimica acta; international journal of clinical chemistry, 325(1-2), 127-131 (2002-10-09)
To determine glycoserum, the nitroblue tetrazolium (NBT) assay is quick, economical, convenient and easily automated. This method, however, is vulnerable to interference by thiol group, which should not be ignored during the analysis. Thiol group in glycoserum was blocked with
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