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Merck
CN

D6413

Sigma-Aldrich

Diloxanide furoate

Synonym(s):

2,2-Dichloro-N-(4-hydroxyphenyl)-N-methylacetamide 2-furoic acid ester

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About This Item

Empirical Formula (Hill Notation):
C14H11Cl2NO4
CAS Number:
3736-81-0
Molecular Weight:
328.15
EC Number:
223-108-1
MDL number:
MFCD00083302
UNSPSC Code:
51101500
PubChem Substance ID:
24894026

Key Documents

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antibiotic activity spectrum

parasites

SMILES string

CN(C(=O)C(Cl)Cl)c1ccc(OC(=O)c2ccco2)cc1

InChI

1S/C14H11Cl2NO4/c1-17(13(18)12(15)16)9-4-6-10(7-5-9)21-14(19)11-3-2-8-20-11/h2-8,12H,1H3

InChI key

BDYYDXJSHYEDGB-UHFFFAOYSA-N

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Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
080H0180

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E Schwartz et al.
Journal of travel medicine, 5(2), 95-96 (1998-10-17)
Hepatitis A virus (HAV) infection and amoebic liver abscess have an identical mode of transmission (fecal-oral route) and similar epidemiology. Either of these diseases might be considered in patients presenting with clinical signs and symptoms of liver disease in areas
Additive effect of diloxanide furoate and metronidazole (Entamizole) in experimental mouse caecal amoebiasis.
K K Bhopale et al.
Indian journal of experimental biology, 33(1), 73-74 (1995-01-01)
[Recommendations for treatment of amebiasis. German Society of Pediatric Infectiology e.V. (DGPI), "Parasitology" Working Group].
S Hohenschild
Klinische Padiatrie, 210(3), 144-145 (1998-06-18)
Cecal ameboma.
Deepak Joshi et al.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 8(1), A28-A28 (2009-03-14)
Tsukasa Fujishima et al.
Chemotherapy, 56(4), 348-352 (2010-08-20)
A mass Entamoeba histolytica infection recurred despite repeated treatments with metronidazole at a rehabilitation institution for individuals with intellectual impairments. Diloxanide furoate was administered to improve intractable intestinal amoebiasis after a recurring amoebic infection that tends to occur via coprophagy
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