D7625
2′-Deoxycytidine 5′-monophosphate sodium salt
≥98%, microbial (fermentation), powder
Synonym(s):
Deoxycytidylic acid, dCMP
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About This Item
Linear Formula:
C9H12N3O7PNa2
CAS Number:
Molecular Weight:
351.16
NACRES:
NA.51
PubChem Substance ID:
UNSPSC Code:
41106305
EC Number:
235-995-2
MDL number:
Assay:
≥98%
Biological source:
microbial (fermentation)
Form:
powder
Storage temp.:
−20°C
Product Name
2′-Deoxycytidine 5′-monophosphate sodium salt, Sigma Grade, ≥98%
InChI key
BLEUYVBRJBDVEH-UHFFFAOYSA-N
InChI
1S/C9H14N3O7P.Na.H/c10-7-1-2-12(9(14)11-7)8-3-5(13)6(19-8)4-18-20(15,16)17;;/h1-2,5-6,8,13H,3-4H2,(H2,10,11,14)(H2,15,16,17);;
SMILES string
[Na].NC1=NC(=O)N(C=C1)C2CC(O)C(COP(O)(O)=O)O2
biological source
microbial (fermentation)
grade
Sigma Grade
assay
≥98%
form
powder
storage temp.
−20°C
Quality Level
Related Categories
Application
2′-Deoxycytidine 5′-monophosphate sodium salt has been used:
- in nucleoside stability studies in human renal cell carcinoma (RCC) cell line SN12C
- in the cell proliferation studies of human intestinal Caco-2 cell line and peripheral blood mononuclear cells (PBMCs)
- as a ligand in dsDNA activation-induced cytidine deaminase crystallization
2′-Deoxycytidine 5-monophosphate (dCMP) is used as a substrate of uridine monophosphate (UMP)/cytidine monophosphate (CMP) kinase (EC 2.7.4.4) to form dCDP which upon phosphorylation to dCTP supports DNA and RNA biosynthesis.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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AID recognizes structured DNA for class switch recombination
Qiao Q, et al.
Molecular Cell, 67(3), 361-373 (2017)
CDA directs metabolism of epigenetic nucleosides revealing a therapeutic window in cancer
Zauri M, et al.
Nature, 524(7563), 114-114 (2015)
Rafael Andrade Caceres et al.
Journal of molecular modeling, 14(5), 427-434 (2008-03-18)
Bacterial cytidylate kinase or cytidine monophosphate kinase (CMP kinase) catalyses the phosphoryl transfer from ATP to CMP and dCMP, resulting in the formation nucleoside diphosphates. In eukaryotes, CMP/UMP kinase catalyses the conversion of UMP and CMP to, respectively, UDP and
Dietary nucleotides and human immune cells. II. Modulation of PBMC growth and cytokine secretion
Holen E, et al.
Nutrition, 22(1), 90-96 (2006)
Dietary nucleotides and intestinal cell lines: I. Modulation of growth
Holen E and Jonsson R
Nutrition Research (New York, N.Y.), 24(3), 197-207 (2004)
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