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Merck
CN

D7662

Delorazepam

Synonym(s):

7-Chloro-5-(o-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one

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About This Item

Empirical Formula (Hill Notation):
C15H10Cl2N2O
CAS Number:
2894-67-9
Molecular Weight:
305.16
UNSPSC Code:
41116107
PubChem Substance ID:
24894151
EC Number:
220-771-9
MDL number:
MFCD00079156

Key Documents

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InChI key

CHIFCDOIPRCHCF-UHFFFAOYSA-N

InChI

1S/C15H10Cl2N2O/c16-9-5-6-13-11(7-9)15(18-8-14(20)19-13)10-3-1-2-4-12(10)17/h1-7H,8H2,(H,19,20)

SMILES string

Clc1ccc2NC(=O)CN=C(c3ccccc3Cl)c2c1

drug control

USDEA Schedule IV; Home Office Schedule 4.1; psychotrope (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; Pszichotróp anyag / Psychotropic Substance (Hungary), 78/2022. (XII. 28.) BM rendelet, kontrollierte Droge in Deutschland

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
veterinary

format

neat

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

German
Dieses Produkt fällt unter das Betäubungsmittelgesetz (BtMG). Für eine Bestellung dieses Produktes ist eine Erlaubnis nach § 3 BtMG zwingend erforderlich, es sei denn, es greift eine Ausnahme von der Erlaubnispflicht nach § 4 oder § 26 BtMG.

English
This product is subject to the German Narcotics Act. A permit under Section 3 of the German Narcotics Act is mandatory for ordering this product unless an exemption from the permit requirement under Section 4 or Section 26 of the German Narcotics Act applies.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

监管及禁止进口产品
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Certificates of Analysis (COA)

Lot/Batch Number
027K4136
105K4059
050K4105
044K4109
120K4071

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[A ketamine-chlordemethyldiazepam combination in celioscopy].
E Struzziero et al.
Minerva ginecologica, 40(12), 715-717 (1988-12-01)
[Use of a chlordemethyldiazepam-fentanyl combination in invasive neuroradiologic examinations].
M Scafuro et al.
Minerva anestesiologica, 54(9), 363-366 (1988-09-01)
Antonella Aresta et al.
Journal of pharmaceutical and biomedical analysis, 28(5), 965-972 (2002-06-01)
An SPME-HPLC-UV method for the determination of delorazepam, a representative benzodiazepine, in spiked human urine samples was developed for the first time. The performances of two commercially available fibers, a carbowax/templated resin (Carbowax/TPR-100) and a polydimethylsiloxane/divinylbenzene (PDMS/DVB), were compared, indicating
I Conti et al.
Research communications in chemical pathology and pharmacology, 67(1), 87-99 (1990-01-01)
In vivo (delorazepam clearance) and in vitro (monooxygenase activity markers) alterations in drug metabolism and the extent of enzyme induction of the hepatic cytochrome P-450 system were evaluated after oral administration of delorazepam (2.5, 25 and 150 mg/kg) for two
R Bolognesi et al.
The American journal of cardiology, 79(2), 242-245 (1997-01-15)
In 2 young adult women who experienced acute heterocyclic antidepressant intoxication, we found a quite unusual electrocardiographic pattern characterized by abnormal ST-tract elevation in the right precordial leads associated with a marked QRS widening (right bundle branch block and left
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