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Merck
CN

D8517

Sigma-Aldrich

Iron–Dextran

95-105 mg/mL (Iron content), solution

Synonym(s):

Ferric hydroxide dextran complex

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
12352201
NACRES:
NA.25
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biological source

synthetic

Quality Level

sterility

aseptically filled

Assay

95-105 mg/mL (Iron content)

form

solution

contains

0.5% phenol as preservative

composition

Iron, ~100 mg/mL

color

brown

useful pH range

4 - 6.5

storage temp.

room temp

SMILES string

[Fe].[S](=O)(=O)(O)O

InChI

1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)

InChI key

MVZXTUSAYBWAAM-UHFFFAOYSA-N

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Application

Iron-Dextran (ferric hydroxide dextran complex) may be used as an intravenous iron delivery preparation. Iron-Dextran may be used to induce iron-overload to study its effects and preventative measures.

Other Notes

To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.

Pictograms

Health hazardExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Carc. 1B - Skin Sens. 1

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Natacha E Piloni et al.
Toxicology, 314(1), 174-182 (2013-10-15)
An in vivo model in rat was developed by intraperitoneally administration of Fe-dextran to study oxidative stress triggered by Fe-overload in rat brain. Total Fe levels, as well as the labile iron pool (LIP) concentration, in brain from rats subjected
Yonggang Gao et al.
Journal of ethnopharmacology, 145(1), 254-260 (2012-11-14)
Danshen (Salvia miltiorrhiza) has been widely prescribed in traditional folk medicine for treatment of hepatic and cardiovascular diseases in China and other Asian countries for several hundred years. Sixty male mice were randomly divided into five groups: control, iron overload
Raymond J Bergeron et al.
Journal of medicinal chemistry, 51(13), 3913-3923 (2008-06-07)
A series of iron-clearing efficiencies (ICEs), ferrokinetics, and toxicity studies for ( S)-2-(2,4-dihydroxyphenyl)-4,5-dihydro-4-methyl-4-thiazolecarboxylic acid (deferitrin, 1), ( S)-4,5-dihydro-2-[2-hydroxy-4-(3,6,9-trioxadecyloxy)phenyl]-4-methyl-4-thiazolecarboxylic acid ( 2), and (S)-4,5-dihydro-2-[2-hydroxy-3-(3,6,9-trioxadecyloxy)phenyl]-4-methyl-4-thiazolecarboxylic acid ( 3) are reported. The ICEs in rodents are shown to be dose-dependent and saturable for
Maureen M Okam et al.
American journal of hematology, 87(11), E123-E124 (2012-09-12)
Oral iron replacement is the standard therapy in iron-deficiency anemia (IDA). However, 59% of patients have gastrointestinal toxicity. With impaired iron uptake from the gastrointestinal tract (in anemia of chronic disease (ACD) or after bariatric surgery), suboptimal responsiveness to exogenous
C Egger et al.
Ultraschall in der Medizin (Stuttgart, Germany : 1980), 33(6), 587-592 (2012-11-17)
To check the feasibility of the easy quantification of tumor vascularization derived from dynamic contrast-enhanced ultrasound (DCE-US) in comparison to dynamic contrast-enhanced computed tomography (DCE-CT) in patients with hepatocellular carcinoma (HCC). 19 patients with cirrhosis and histologically proven HCC prospectively

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