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D9069

N-Desmethyltamoxifen HCl

Name: N-Desmethyltamoxifen HCl
Brand: SIGMA

≥98% (HPLC), solid

Synonym(s):

(Z)-2-(p-(1,2-Diphenyl-1-butenyl)phenoxy)-N-methylethylamine, ICI 55,548

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About This Item

Empirical Formula (Hill Notation):

C₂₅H₂₇NO·HCl

CAS Number:

15917-65-4

Molecular Weight:

393.95

NACRES:

NA.77

PubChem Substance ID:

329798889

UNSPSC Code:

12352203

MDL number:

MFCD03423594

Assay:

≥98% (HPLC)

Form:

solid

Storage condition:

desiccated

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Properties

sterility

non-sterile

Quality Segment

100

assay

≥98% (HPLC)

form

solid

storage condition

desiccated

technique(s)

inhibition assay: suitable

solubility

DMSO: ≥20 mg/mL

shipped in

ambient

storage temp.

room temp

SMILES string

Cl.CC\C(c1ccccc1)=C(/c2ccccc2)c3ccc(OCCNC)cc3

InChI

1S/C25H27NO.ClH/c1-3-24(20-10-6-4-7-11-20)25(21-12-8-5-9-13-21)22-14-16-23(17-15-22)27-19-18-26-2;/h4-17,26H,3,18-19H2,1-2H3;1H/b25-24-;

InChI key

GMLHJWZEYLTNJW-BJFQDICYSA-N

Description

Application

N-Desmethyltamoxifen HCl has been used as an internal standard in high-performance liquid chromatography (HPLC) for the quantification of metabolites from NG2 cell-derived astrocytes.

Biochem/physiol Actions

N-Desmethyltamoxifen HCl is the primary metabolite of tamoxifen. N-Desmethyltamoxifen HCl is an estrogen response modifer and protein kinase C inhibitor.

Features and Benefits

This compound is featured on the Nuclear Receptors (Steroids) and PKC pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Pictograms

GHS08,GHS09

Signal Word

Danger

Hazard Codes

H350,H360,H410

Precautionary Statements

P202 - P273 - P280 - P308 + P313 - P391 - P405

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B - Repr. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)